메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
김윤홍 (고신대학교) 김부경 (고신대학교) 김기현 (고신대학교) 서경원 (고신대학교) 정경원 (고신대학교) 박선자 (고신대학교) 임상현 ((주)쎌바이오텍) 손두헌 ((주)쎌바이오텍) 김재현 (고신대학교)
저널정보
대한내분비학회 Endocrinology and Metabolism Endocrinology and Metabolism Vol.37 No.3
발행연도
2022.6
수록면
475 - 486 (12page)
DOI
https://doi.org/10.3803/EnM.2022.1481

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background: Current evidence support that the gut microbiota plays a potential role in obesity. Bariatric surgery can reduce excessweight and decrease the risk of life-threatening weight-related health problems and may also influence gut microbiota. In this study,we aimed to investigate the changes in gut microbiota before and after bariatric surgery and evaluate the association of the gut microbial shift and altered body mass index (BMI) after bariatric surgery. Methods: Between January 2019 and July 2020, stools from 58 patients scheduled for bariatric surgery were collected. Six monthsafter bariatric surgery, stools from 22 of these patients were re-collected, and the changes in gut microbiota before and after bariatricsurgery were evaluated. In addition, the differences in gut microbiota between patients with severe obesity (BMI >35 kg/m2, n=42)and healthy volunteers with normal BMI (18.8 to 22.8 kg/m2, n=41) were investigated. Results: The gut microbiota of patients who underwent bariatric surgery showed increased α-diversity and differed β-diversity compared with those before surgery. Interestingly, Blautia was decreased and Bacteriodes was increased at the genus level after bariatricsurgery. Further, the Blautia/Bacteroides ratio showed a positive correlation with BMI. To validate these results, we compared thegut microbiota from severely obese patients with high BMI with those from healthy volunteers and demonstrated that the Blautia/Bacteroides ratio correlated positively with BMI. Conclusion: In the gut microbial analysis of patients who underwent bariatric surgery, we presented that the Blautia/Bacteroides ratio had changed after bariatric surgery and showed a positive correlation with BMI.

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0