지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.4
- 수록면
- 147 - 153 (7page)
- DOI
- 10.3341/kjo.2021.0164
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초록· 키워드
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Purpose: To identify clinical factors associated with the early reduction of corneal sensitivity (CS) in patients with herpes zosterophthalmicus (HZO).Methods: Total 30 subjects were divided into two groups according to the occurrence of an early reduction of CS (group 1,normal CS; group 2, decreased CS). The demographics, ocular manifestations of HZO, and the ocular surface parameters werecompared between two groups. Then, the relative risks of variables were analyzed to expect the early decrease of CS by HZOusing logistic regression analysis.Results: Among total 30 subjects, the CS decreased in 10 subjects (3.2 ± 1.4 cm, group 2) and the other 20 subjects revealednormal CS (6.0 ± 0.0 cm, group 1). The age was higher in the group 2 (67.0 ± 16.6 years) than in group 1 (48.0 ± 17.6 years,p = 0.013), but sex and the comorbidity of diabetes mellitus was not difference between groups. The presence of cornealpunctate epithelial erosions was a single factor among the ocular manifestations of HZO, which discriminated group 1 (5%)and group 2 (60%, p = 0.002). The ocular surface staining scores (i.e., National Eye Institute scores and Sjogren’s InternationalCollaborative Clinical Alliance ocular surface score) were higher in group 2 (p = 0.001 and p = 0.021, respectively) than ingroup 1. The existence of corneal punctate epithelial erosions revealed as a sole risk factor for the early reduction of CS (oddsratio = 33.085; p = 0.016).Conclusions: It is necessary to pay attention to the possible occurrence of neurotrophic keratopathy especially in older patientswith HZO showing an initial presence of corneal punctate epithelial erosions.
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