Parathyroid Crisis as Presentation of Atypical Parathyroid Adenoma: Two Diagnostically Challenging Cases

Balcázar-Hernández Lourdes; Alexis Trejo Montes; Tania Islem Gamboa Jimenéz; Vargas-Ortega Guadalupe; González-Virla Baldomero; Balcázar-Hernández Lourdes

추천

검색

자료유형: 학술저널

저자정보: Balcázar-Hernández Lourdes (Department of Endocrinology Hospital de Especialidades Centro Médico Nacional Siglo XXI) Alexis Trejo Montes (Hospital de Especialidades) Tania Islem Gamboa Jimenéz (Hospital de Especialidades) Vargas-Ortega Guadalupe (Hospital de Especialidades) González-Virla Baldomero (Hospital de Especialidades) Balcázar-Hernández Lourdes (Hospital de Especialidades)

저널정보: 대한골대사학회 대한골대사학회지 대한골대사학회지 제29권 제2호

발행연도: 2022.5

수록면: 133 - 140 (8page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Atypical parathyroid adenoma (APA) is a rare cause of primary hyperparathyroidism (PHPT) and represents a diagnostic challenge since it is an intermediate form of parathyroid neoplasm of uncertain malignant potential with atypical histological features that require differential diagnosis of parathyroid carcinoma (PC). We present 2 cases of parathyroid crisis as a presentation of APA. The first case was that of a 56-year-old man with parathyroid crisis, constitutional syndrome, and anemia, with evidence of APA after en bloc resection, evolving with hungry bone syndrome after surgery and curation criteria at 6 months after parathyroidectomy (PTX). The second case was a 64-year-old woman with acute chronic kidney disease and parathyroid crisis, with evidence of APA after selective PTX and >50% reduction in parathyroid hormone levels after surgery; however, persistent PHPT at 6 months post-surgery was observed. These cases represented a diagnostic challenge due to their rare clinical presentation (parathyroid crisis), with a heterogeneous spectrum of target organ damage and infrequent symptoms (constitutional syndrome and acute chronic renal disease), in turn caused by a rare pathology (APA). The presentation of these patients may be indicative of PC; however, histopathological diagnosis is a key to the diagnosis of APA. The differential diagnosis of APA vs. PC in clinical practice is indispensable.

#Adenoma · Hypercalcemia · Hyperparathyroidism · Primary · Parathyroid neoplasm

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!