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논문 기본 정보

자료유형
학술저널
저자정보
Pham Thuy Thu (Adult Congenital Heart Disease Unit Vietnam National Heart Institute BachMai Hospital Hanoi Vietnam) Nguyen Hoai Thi Thu (Adult Congenital Heart Disease Unit Vietnam National Heart Institute BachMai Hospital Hanoi Vietnam)
저널정보
아시아심장혈관영상의학회 Cardiovascular Imaging Asia Cardiovascular Imaging Asia Vol.6 No.2
발행연도
2022.4
수록면
41 - 48 (8page)
DOI
10.22468/cvia.2021.00332

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Objective: The aim of our study was to evaluate the global and regional free wall longitudinal strains of the right ventricle (RV) to detect RV dysfunction in congenital heart disease (CHD) patients with pulmonary arterial hypertension (PAH). Materials and Methods: Seventy CHD patients with PAH and 30 normal controls were enrolled in this study. Patients were placed into three subgroups including patients with pretricuspid shunt Eisenmenger syndrome (ES) (Group A), patients with post- tricuspid shunt ES (Group B), and patients with non-fixed PAH (Group C). The World Health Organization functional classification (WHO FC) was used to functionally classify the study population. RV free wall strain (FWS); regional RV strains of apical, mid, basal FWS; and RV global longitudinal strain (GLS) were measured by 2D speckle tracking echocardiography (STE), while other parameters were measured by conventional echocardiography. Results: Forty-three patients (61.4%) were classified as WHO FC III or greater. Mean RVFWS and RVGLS were -20.42%±5.9% and -17.62%±5.5%, respectively. All RV strains including regional FWS were lower in patients compared with healthy controls (p<0.001). RV strains exhibited a higher rate of RV dysfunction compared to the conventional parameters. Mean RVGLS and RVFWS in the two ES groups were lower compared to that in Group C (p<0.001). Within regional trains, basal FWS in Group C was higher than in Group A (p<0.001) but similar to that of Group B. RVFWS, RVGLS, and regional FWS significantly correlated with pulmonary arterial systolic pressure and WHO FC. Conclusion: In CHD with PAH, 2D-STE parameters are potentially more capable of early detection of RV dysfunction than are conventional echo indices.

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