메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Lee Hye Mi (Leehyemi Plastic Surgery Clinic) Kim Choon Soo (Department of Plastic and Reconstructive Surgery Wonkwang University Hospital) 나영천 (Department of Plastic and Reconstructive Surgery, Wonkwang University Hospital) 윤치선 (Department of Plastic and Reconstructive Surgery, Wonkwang University Hospital) Jong Hwan Kim (Department of Plastic and Reconstructive Surgery Wonkwang University Hospital) Seon Sik Yun (Department of Plastic and Reconstructive Surgery Yonsei University College of Medicine) Park Ji Hye (Brain Research Institute Wonkwang University)
저널정보
대한창상학회 Journal of Wound Management and Research Journal of Wound Management and Research Vol.18 No.1
발행연도
2022.2
수록면
11 - 16 (6page)
DOI
10.22467/jwmr.2021.01823

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background: Particulate matter (PM) is known to increase the risk of diseases in major organs and PM may also slow the complex process of wound healing. We investigated the effect of PM on wound healing in vivo. Methods: Twelve 10-week-old Sprague-Dawley male rats were punctured with three 8 mm-diameter holes each in the skin on their backs. The holes were divided into three groups according to treatment: PM 50 μg/mL (group A), PM 100 μg/mL (group B) and saline (control). For histologic analysis, three rats were sacrificed on each of the 1st, 3rd, 7th, and 28th days, and a total of 36 samples were collected. Inflammatory cell infiltration and neovascularization were evaluated for comparison among groups. Results: Inflammation increased in groups A and B on day 1, but no significance was observed. On the 28th day, increased inflammation was observed in groups A and B compared to the control group, with significant difference. Angiogenesis increased in groups A and B compared to the control group on day 1, but no significance was observed. On the 3rd day, there was a decrease in group B, with statistical significance. On day 28, it was observed that angiogenesis significantly increased in group B compared to the control group. Conclusion: Inflammation increased in the PM groups compared with the control group and angiogenesis decreased, then slowly increased in the PM groups compared with the control group. Our findings suggest that PM increases inflammation and delays angiogenesis in the wound healing process.

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0