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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한임상검사정도관리협회 Journal of Laboratory Medicine And Quality Assurance Laboratory Medicine and Quality Assurance 제44권 제1호
- 발행연도
- 2022.3
- 수록면
- 36 - 39 (4page)
- DOI
- 10.15263/jlmqa.2022.44.1.36
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초록· 키워드
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Background: With the increase in multidrug-resistant (MDR) gram-negative rods, colistin treatment is increasingly required. Reliable susceptibility testing is important for managing infectious patients with MDR Pseudomonas aeruginosa . This study evaluated the reliability of an automated colistin susceptibility assay.
Methods: In total, 195 non-duplicated P. aeruginosa blood isolates were collected from nine sentinel hospitals in Korea in 2020. Colistin susceptibility with Sensititre KNIHCOL Trek diagnostic system (Thermo Fisher Scientific, England), a commercial broth microdilution (BMD), was compared with that of the gram-negative MIC panel type 44 card (Beckman Coulter, USA). Isolates with discrepant results were reconfirmed using AST-N225 (bioMerieux SA, France).
Results: Categorical agreement was 92.8%, and nine colistin-resistant isolates with BMD were colistin-intermediate with two automated colistin susceptibility assays.
Conclusions: The failure to detect colistin-resistant P. aeruginosa could not be safely excluded with an automated colistin susceptibility assay.
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