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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국약제학회 Journal of Pharmaceutical Investigation Journal of Pharmaceutical Investigation 제48권 제3호
- 발행연도
- 2018.5
- 수록면
- 233 - 241 (9page)
- DOI
- 10.1007/s40005-017-0353-5
이용수
초록· 키워드
오류제보하기
Cardiovascular diseases are the leading cause of death, and dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease. During the last several decades, development of drugs that reduce low density lipoprotein- cholesterol has been the focus in the treatment and prevention of dyslipidemia and cardiovascular diseases. In addition, statins and other cholesterol-reducing drugs have been the standard of treatment for dyslipidemia. Triglyceride (TG)-rich lipoproteins are also a significant risk factor for atherosclerosis and cardiovascular diseases, and pharmacological strategies to control TG-rich lipoproteins are now attracting much interest. In this review, mediators of lipoprotein metabolism and current therapeutic strategies with the formulation designs are discussed and new candidate therapeutic targets are presented.
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등록된 정보가 없습니다.
참고문헌 (89)
참고문헌 신청
Abifadel M / 2003 / Mutations in PCSK9 cause autosomal dominant hypercholesterolemia / Nat Genet 34:154~156
Abo Enin HA / 2015 / Self-nanoemulsifying drug-delivery system for improved oral bioavailability of rosuvastatin using natural oil antihyperlipdemic / Drug Dev Ind Pharm 41:1047~1056
Altmann SW / 2004 / Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption / Science 303:1201~1204
Assmann G / 2002 / Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the Prospective Cardiovascular Munster (PROCAM) study / Circulation 105:310~315
Bakker-Arkema RG / 1996 / Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia / JAMA 275:128~133
Abo Enin HA / 2015 / Self-nanoemulsifying drug-delivery system for improved oral bioavailability of rosuvastatin using natural oil antihyperlipdemic / Drug Dev Ind Pharm 41:1047~1056
Altmann SW / 2004 / Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption / Science 303:1201~1204
Assmann G / 2002 / Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the Prospective Cardiovascular Munster (PROCAM) study / Circulation 105:310~315
Bakker-Arkema RG / 1996 / Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia / JAMA 275:128~133
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