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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 520 - 534 (15page)
- DOI
- https://doi.org/10.4111/icu.20210254
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초록· 키워드
오류제보하기
Purpose: To assess the effects of Serenoa repens alone or in combination with other phytotherapy compared to placebo in men with LUTS due to benign prostatic enlargement.
Materials and Methods: Following a registered protocol (CRD42021226655), we searched (December 2020) MEDLINE, CENTRAL, Embase, ClinicalTrials.gov, WHO-ICTRP trials platform and other sources with no restrictions on language, publication date or status. We included randomized controlled trials, and we critically appraised them using the Cochrane Tool for Risk of Bias Assessment (RoB 2). We conducted random-effects meta-analysis when appropriate. The primary outcomes included urinary symptoms score, quality of life, and adverse events. The certainty of the evidence was rated using GRADE.
Results: We included 27 trials with 4,853 participants. S. repens results in little to no difference in urinary symptoms, quality of life, and adverse events at short- and long-term follow-up. S. repens combined with other phytotherapy may slightly reduce urinary symptoms at short-term follow-up, but the results are uncertain. The results on quality of life and adverse events are also very uncertain.
Conclusions: S. repens alone may result in no clinical benefits for men with LUTS. There is greater uncertainty in the effects of S. repens in combination with other phytotherapy.
목차
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참고문헌 (77)
참고문헌 신청
Garraway WM / 1991 / High prevalence of benign prostatic hypertrophy in the community / Lancet 338:469~471
Berry SJ / 1984 / The development of human benign prostatic hyperplasia with age / J Urol 132:474~479
Launer BM / 2021 / The rising worldwide impact of benign prostatic hyperplasia / BJU Int 127:722~728
Gravas S / EAU guidelines on management of nonneurogenic male lower urinary tract symptoms (LUTS), incl. benign prostatic obstruction (BPO)
AUA Practice Guidelines Committee / 2003 / AUA guideline on management of benign prostatic hyperplasia (2003). Chapter 1:diagnosis and treatment recommendations / J Urol. 170(2Pt 1):530~547
Berry SJ / 1984 / The development of human benign prostatic hyperplasia with age / J Urol 132:474~479
Launer BM / 2021 / The rising worldwide impact of benign prostatic hyperplasia / BJU Int 127:722~728
Gravas S / EAU guidelines on management of nonneurogenic male lower urinary tract symptoms (LUTS), incl. benign prostatic obstruction (BPO)
AUA Practice Guidelines Committee / 2003 / AUA guideline on management of benign prostatic hyperplasia (2003). Chapter 1:diagnosis and treatment recommendations / J Urol. 170(2Pt 1):530~547
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