두피 혈관육종(Scalp Angiosarcoma)의 치료 성적: 단일 기관의 경험

류성석; 박승진; 정영호; 최승호; 남순열; 김상윤; 이윤세

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자료유형: 학술저널

저자정보: 류성석 (울산대학교 의과대학 서울아산병원 이비인후과학교실) 박승진 (울산대학교 의과대학 강릉아산병원 이비인후과학교실) 정영호 (울산대학교 의과대학 서울아산병원 이비인후과학교실) 최승호 (울산대학교) 남순열 (울산대학교) 김상윤 (울산대학교) 이윤세 (울산대학교)

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후-두경부외과학회지 제64권 제9호

발행연도: 2021.9

수록면: 652 - 658 (7page)

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Background and Objectives Scalp angiosarcoma is a rare but aggressive vascular malignancy. It is often found in the advanced state and tends to cause distant metastasis at an earlystage. There is no consensus on a treatment modality, although wide excision followed by adjuvanttherapy is currently used. The purpose of this study was to analyze the treatment resultsand disease progress pattern of scalp angiosarcoma in a single institution. Subjects and Method We enrolled patients who diagnosed with scalp angiosarcoma atAsan Medical Center from March 2011 to September 2019. Disease course and prognostic factorswere analyzed by estimating overall survival rate and disease free survival. Results A total 12 patients were enrolled in this study. The median overall survival was 16.0months. The 3-year-survival rate was 10.6%, and the median disease free survival was 5.0months. On the average, it took 11.4 months till death after recurrence. Conclusion Although wide surgical excision and multiple adjuvant therapies are employed,scalp angiosarcoma showed frequent recurrences and metastasis which led to poor outcomes. Further investigations for scalp angiosarcoma are necessary to improve treatment outcomes.

#Head and neck cancer #Hemangiosarcoma #Radiation therapy #Scalp #Surgery #Survival rate.

참고문헌 (29)

참고문헌 신청

Fury MG / 2005 / A 14-year retrospective review of angiosarcoma: Clinical characteristics, prognostic factors, and treatment outcomes with surgery and chemotherapy / Cancer J 11(3):241~247

Gudewer E / 2009 / Widespread cutaneous angiosarcoma of the scalp : Diagnosis and soft tissue reconstruction with a combined double-muscle-free flap and split-thickness-skin graft / Oral Maxillofac Surg 13(2):95~98

Sasaki R / 2002 / Angiosarcoma treated with radiotherapy : Impact of tumor type and size on outcome / Int J Radiat Oncol Biol Phys 52(4):1032~1040

Holden CA / 1987 / Angiosarcoma of the face and scalp, prognosis and treatment / Cancer 59(5):1046~1057

Chen KT / 1979 / Angiosarcoma following therapeutic irradiation / Cancer 44(6):2044~2048

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