지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.7
- 수록면
- 793 - 799 (7page)
- DOI
- 10.3349/ymj.2017.58.4.793
이용수
초록· 키워드
오류제보하기
Purpose: Investigating the risk of vascular access failure is critical for maintenance hemodialysis (MHD) patients. Erythropoietin stimulating agents (ESA) typically used for anemia of chronic kidney disease (CKD) may also stimulate neointimal hyperplasia, which is the most important factor in late arteriovenous fistula (AVF) failure. The aim of this study was to investigate whether ESA treatment is associated with late AVF failure.
Materials and Methods: The late AVF failure group comprised 51 patients who underwent percutaneous intervention or surgery for fistula revision after successful use for at least three months. There were 51 controls whose AVF had been patent for at least 24 months.
Results: The mean time from the first cannulation to late loss of AVF patency was 8.4±4.2 months. The average weekly dose of ESA was significantly higher in patients with AVF failure (4782.2±2360.5 IU/mL/wk vs. 7161.8±2775.2 IU/mL/wk, p<0.001). The only independentpredictor of late AVF failure in multivariate analysis was high average ESA dose (odds ratio=1.015, 95% confidence interval=1.002?1.028, p=0.022).
Conclusion: Patients with late AVF patency loss exhibit an association with a higher dose of ESA, although causality is unproven. Further study to elucidate potential mechanisms is warranted.
목차
등록된 정보가 없습니다.
참고문헌 (37)
참고문헌 신청
Leermakers JJ / 2013 / Cost-effectiveness of vascular access for haemodialysis:arteriovenous fistulas versus arteriovenous grafts / Eur J Vasc Endovasc Surg 45:84~92
Rosas SE / 2012 / Synthetic vascular hemodialysis access versus native arteriovenous fistula: a cost-utility analysis / Ann Surg 255:181~186
Roy-Chaudhury P / 2006 / Hemodialysis vascular access dysfunction: a cellular and molecular viewpoint / J Am Soc Nephrol 17:1112~1127
Beathard GA / Failure of the mature hemodialysis arteriovenous fistula
Lu FP / 2015 / One-year patency rate of native arteriovenous fistulas reconstructed by vascular stripping in hemodialysis patients with venous neointimal hyperplasia / J Vasc Surg 61:192~196
Rosas SE / 2012 / Synthetic vascular hemodialysis access versus native arteriovenous fistula: a cost-utility analysis / Ann Surg 255:181~186
Roy-Chaudhury P / 2006 / Hemodialysis vascular access dysfunction: a cellular and molecular viewpoint / J Am Soc Nephrol 17:1112~1127
Beathard GA / Failure of the mature hemodialysis arteriovenous fistula
Lu FP / 2015 / One-year patency rate of native arteriovenous fistulas reconstructed by vascular stripping in hemodialysis patients with venous neointimal hyperplasia / J Vasc Surg 61:192~196
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