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학술저널
저자정보
Ya-Lin Kong (Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University) Ying Xing (Department of General Surgery Tiantan Hospital Affiliated to Capital Medical University China) Jie Li (Department of Hepatobiliary Surgery Zibo Central Hospital China.) Cheng-Li Liu (Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University) Xiao-Jun He (Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University) Cheng Wang (Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University) Jiang-Min Chen (Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University) Ling-Hong Kong (Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University) Xu Han (Department of Hepatobiliary Surgery Zibo Central Hospital China.) Hong-Yi Zhang (Tiantan Hospital Affiliated to Capital Medical University)
저널정보
연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제62권 제10호
발행연도
2021.10
수록면
918 - 927 (10page)
DOI
10.3349/ymj.2021.62.10.918

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Purpose: We compared the clinical outcomes of modified procedures for associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) based on a risk-reduced strategy with those of classic ALPPS procedures in treating large liver carcinoma. Materials and Methods: Short-term outcomes, increases in future liver remnant (FLR) and functional FLR (FFLR), and overall survival (OS) were compared between 45 consecutive patients treated with modified ALPPS procedures and 34 patients treated with classic ALPPS procedures. Results: Clinical outcomes after the 1st-stage operation markedly improved with the modified procedures. Although the proportions of liver cirrhosis and hepatocellular carcinoma were higher in the modified group, the mortality and incidence of severe complications did not increase. FLR and FFLR hypertrophy at 1 week after the 1st-stage operation were similar in both groups; however, kinetic growth rates in the modified group were lower. OS rates were similar. Conclusion: Modified ALPPS procedures could be safely applied to provide long-term survival for patients with liver cirrhosis without sufficient FLR.

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