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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 961 - 968 (8page)
- DOI
- 10.3349/ymj.2021.62.11.961
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초록· 키워드
오류제보하기
Since the COVID-19 pandemic first began in December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has continuously evolved with many variants emerging across the world. These variants are categorized as the variant of interest (VOI), variant of concern (VOC), and variant under monitoring (VUM). As of September 15, 2021, there are four SARS-CoV-2 lineages designated as the VOC (alpha, beta, gamma, and delta variants). VOCs have increased transmissibility compared to the original virus, and have the potential for increasing disease severity. In addition, VOCs exhibit decreased susceptibility to vaccineinduced and infection-induced immune responses, and thus possess the ability to reinfect previously infected and recovered individuals. Given their ability to evade immune responses, VOC are less susceptible to monoclonal antibody treatments. VOCs can also impact the effectiveness of mRNA and adenovirus vector vaccines, although the currently authorized COVID-19 vaccines are still effective in preventing infection and severe disease. Current measures to reduce transmission as well as efforts to monitor andunderstand the impact of variants should be continued. Here, we review the molecular features, epidemiology, impact on transmissibility, disease severity, and vaccine effectiveness of VOCs.
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참고문헌 (61)
참고문헌 신청
Sui J / 2008 / Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway / PLoS Pathog 4:e1000197
Gupta RK / 2021 / Will SARS-CoV-2 variants of concern affect the promise of vaccines? / Nat Rev Immunol 21:340~341
Avanzato VA / 2020 / Case study : prolonged infectious SARS-CoV-2 shedding from an asymptomatic immunocompromised individual with cancer / Cell 183:1901~1912
Kemp SA / 2021 / SARS-CoV-2 evolution during treatment of chronic infection / Nature 592:277~282
Groves DC / 2021 / The D614G mutations in the SARS-CoV-2 spike protein : implications for viral infectivity, disease severity and vaccine design / Biochem Biophys Res Commun 538:104~107
Gupta RK / 2021 / Will SARS-CoV-2 variants of concern affect the promise of vaccines? / Nat Rev Immunol 21:340~341
Avanzato VA / 2020 / Case study : prolonged infectious SARS-CoV-2 shedding from an asymptomatic immunocompromised individual with cancer / Cell 183:1901~1912
Kemp SA / 2021 / SARS-CoV-2 evolution during treatment of chronic infection / Nature 592:277~282
Groves DC / 2021 / The D614G mutations in the SARS-CoV-2 spike protein : implications for viral infectivity, disease severity and vaccine design / Biochem Biophys Res Commun 538:104~107
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