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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국의학물리학회 의학물리 의학물리 제32권 제4호
- 발행연도
- 2021.12
- 수록면
- 172 - 178 (7page)
- DOI
- 10.14316/pmp.2021.32.4.172
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초록· 키워드
오류제보하기
Purpose: This study aimed to develop a deep learning architecture combining two task models to generate synthetic computed tomography (sCT) images from low-tesla magnetic resonance (MR) images to improve metallic marker visibility.
Methods: Twenty-three patients with cervical cancer treated with intracavitary radiotherapy (ICR) were retrospectively enrolled, and images were acquired using both a computed tomography (CT) scanner and a low-tesla MR machine. The CT images were aligned to the corresponding MR images using a deformable registration, and the metallic dummy source markers were delineated using threshold-based segmentation followed by manual modification. The deformed CT (dCT), MR, and segmentation mask pairs were used for training and testing. The sCT generation model has a cascaded three-dimensional (3D) U-Net-based architecture that converts MR images to CT images and segments the metallic marker. The performance of the model was evaluated with intensity-based comparison metrics.
Results: The proposed model with segmentation loss outperformed the 3D U-Net in terms of errors between the sCT and dCT. The structural similarity score difference was not significant. Conclusions: Our study shows the two-task-based deep learning models for generating the sCT images using low-tesla MR images for 3D ICR. This approach will be useful to the MR-only workflow in high-dose-rate brachytherapy.
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참고문헌 (20)
참고문헌 신청
Chargari C / 2009 / Physics contributions and clinical outcome with 3D-MRI-based pulsed-dose-rate intracavitary brachytherapy in cervical cancer patients / Int J Radiat Oncol Biol Phys 74:133~139
Tanderup K / 2014 / Curative radiation therapy for locally advanced cervical cancer : brachytherapy is NOT optional / Int J Radiat Oncol Biol Phys 88:537~539
Chassagne D / 1985 / Report No. 38: dose and volume specification for reporting intracavitary therapy in gynecology :20
Kang HC / 2010 / 3D CT-based highdose-rate brachytherapy for cervical cancer : clinical impact on late rectal bleeding and local control / Radiother Oncol 97:507~513
Pötter R / 2006 / Recommendations from gynaecological(GYN)GEC ESTRO working group(II) : concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology / Radiother Oncol 78:67~77
Tanderup K / 2014 / Curative radiation therapy for locally advanced cervical cancer : brachytherapy is NOT optional / Int J Radiat Oncol Biol Phys 88:537~539
Chassagne D / 1985 / Report No. 38: dose and volume specification for reporting intracavitary therapy in gynecology :20
Kang HC / 2010 / 3D CT-based highdose-rate brachytherapy for cervical cancer : clinical impact on late rectal bleeding and local control / Radiother Oncol 97:507~513
Pötter R / 2006 / Recommendations from gynaecological(GYN)GEC ESTRO working group(II) : concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology / Radiother Oncol 78:67~77
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