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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 988 - 996 (9page)
- DOI
- https://doi.org/10.3803/EnM.2021.1107
이용수
초록· 키워드
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Background: We investigated how 100-g oral glucose tolerance test (OGTT) results can be used to predict adverse pregnancy outcomes in gestational diabetes mellitus (GDM) patients.
Methods: We analyzed 1,059 pregnant women who completed the 100-g OGTT between 24 and 28 weeks of gestation. We compared the risk of adverse pregnancy outcomes according to OGTT patterns by latent profile analysis (LPA), numbers to meet theOGTT criteria, and area under the curve (AUC) of the OGTT graph. Adverse pregnancy outcomes were defined as a composite ofpreterm birth, macrosomia, large for gestational age, low APGAR score at 1 minute, and pregnancy-induced hypertension.
Results: Overall, 257 participants were diagnosed with GDM, with a median age of 34 years. An LPA led to three different clusters ofOGTT patterns; however, there were no significant associations between the clusters and adverse pregnancy outcomes after adjustingfor confounders. Notwithstanding, the risk of adverse pregnancy outcome increased with an increase in number to meet the OGTTcriteria (P for trend=0.011); odds ratios in a full adjustment model were 1.27 (95% confidence interval [CI], 0.72 to 2.23), 2.16 (95%CI, 1.21 to 3.85), and 2.32 (95% CI, 0.66 to 8.15) in those meeting the 2, 3, and 4 criteria, respectively. The AUCs of the OGTT curvesalso distinguished the patients at risk of adverse pregnancy outcomes; the larger the AUC, the higher the risk (P for trend=0.007).
Conclusion: The total number of abnormal values and calculated AUCs for the 100-g OGTT may facilitate tailored management ofpatients with GDM by predicting adverse pregnancy outcomes.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
American Diabetes Association / 2020 / 6. Glycemic targets : standards of medical care in diabetes-2020 / Diabetes Care 43(Suppl 1):S66~76
Magliano DJ / 2019 / Trends in incidence of total or type 2diabetes: systematic review / BMJ 366:l5003
World Health Organization / Diabetes
김보연 / 2019 / Diabetes Fact Sheets in Korea, 2018: An Appraisal of Current Status / Diabetes and Metabolism Journal 43(4):487~494
Carpenter MW / 1982 / Criteria for screening tests for gestational diabetes / Am J Obstet Gynecol 144:768~773
Magliano DJ / 2019 / Trends in incidence of total or type 2diabetes: systematic review / BMJ 366:l5003
World Health Organization / Diabetes
김보연 / 2019 / Diabetes Fact Sheets in Korea, 2018: An Appraisal of Current Status / Diabetes and Metabolism Journal 43(4):487~494
Carpenter MW / 1982 / Criteria for screening tests for gestational diabetes / Am J Obstet Gynecol 144:768~773
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