지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.8
- 수록면
- 67 - 88 (22page)
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초록· 키워드
오류제보하기
Objectives The purpose of this study is to analyze randomized clinical trials (RCTs) on traditional Chinese medicine to summarize its efficacy and safety for the treatment of functional gastrointestinal disorders (FGIDs) in children.
Methods We searched literatures published up to March 19, 2021 using two Chinese electronic databases. Data regarding patients, interventions, results, and adverse events were extracted from RCTs of herbal medicine for children with FGIDs.
Results A total of 34 RCTs were included: 16 trials on functional dyspepsia, 7 trials on functional constipation, 6 trials on functional abdominal pain, 4 trials on irritable bowel syndrome, and 1 trial on functional diarrhea. 26 of 29 trials that reported total effective rate, the treatment group showed a significant improvement compared to the control group. Most of other evaluation indicators, such as symptom score, symptom disappearance time, and recurrence rate also demonstrated statistically significant improvement. Of the 16 studies which reported safety, 5 studies reported no adverse reactions in either group, and 4 studies reported no statistically significant differences in the incidence of adverse events between two groups. Also, reported adverse events were mostly mild.
Conclusions Herbal medicine may help improve symptoms of FGIDs in children. However, due to limited types of studies on sub-diseases of FGIDs and small sample sizes in each study, additional large scale clinical studies on various other FGIDs are necessary.
목차
등록된 정보가 없습니다.
참고문헌 (45)
참고문헌 신청
Drossman DA / 2016 / Rome IV—functional GI disorders : disorders of gut-brain interaction / Gastroenterol 150(6):1257~1261
Tadayuki Oshima / 2015 / Epidemiology of Functional Gastrointestinal Disorders in Japan and in the World / Journal of Neurogastroenterology and Motility (JNM) 21(3):320~329
Drossman DA / 2016 / Functional gastrointestinal disorders : history, pathophysiology, clinical features, and Rome IV / Gastroenterol 150(6):1262~1279
류한승 / 2017 / 로마 기준 IV 이해하기: 로마 기준 IV 개정의 배경 / 대한내과학회지 92(4):349~353
Varni JW / 2015 / Pediatric quality of life inventory (PedsQL) gastrointestinal symptoms module testing study consortium. Health-related quality of life in pediatric patients with functional and organic gastrointestinal diseases / J Pediatr 166(1):85~90
Tadayuki Oshima / 2015 / Epidemiology of Functional Gastrointestinal Disorders in Japan and in the World / Journal of Neurogastroenterology and Motility (JNM) 21(3):320~329
Drossman DA / 2016 / Functional gastrointestinal disorders : history, pathophysiology, clinical features, and Rome IV / Gastroenterol 150(6):1262~1279
류한승 / 2017 / 로마 기준 IV 이해하기: 로마 기준 IV 개정의 배경 / 대한내과학회지 92(4):349~353
Varni JW / 2015 / Pediatric quality of life inventory (PedsQL) gastrointestinal symptoms module testing study consortium. Health-related quality of life in pediatric patients with functional and organic gastrointestinal diseases / J Pediatr 166(1):85~90
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