지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.6
- 수록면
- 128 - 136 (9page)
- DOI
- 10.5213/inj.2040304.152
이용수
초록· 키워드
오류제보하기
Purpose: The present study determined the effects of saphenous nerve stimulation (SNS) at different stimulation frequencies on bladder reflex and explored a possible action mechanism of tibial nerve stimulation (TNS) on bladder activity in cats.
Methods: Two bipolar nerve cuff electrodes were implanted on the saphenous nerve and the contralateral tibial nerve in 13 cats, respectively. Multiple cystometrograms were obtained to determine the effects of single SNS at different frequencies and that of combined SNS and TNS on the micturition reflex by infusing normal saline.
Results: SNS at 1 Hz significantly reduced the bladder capacity (BC) to 59.8%±7.7% and 59.3%±5.8% of the control level at the intensity threshold (T) and 2T, respectively (P<0.05), while that at 20 Hz significantly increased the BC to 130.6%±4.2% of the control level at 6T (P<0.05). The TNS and SNS at 20 Hz did not significantly change the BCs at 1T (P>0.05), while combined stimulation at 1T significantly increased the BC to 122.7%±1.9% of the control level and induced an inhibitory effect which was similar to that TNS at 2T.
Conclusions: The current study revealed that SNS reduced and increased BC depending on different stimulation frequencies.
The combined SNS and TNS maximized the clinical efficacy at a low intensity. Also, SNS may be a potential therapeutic mechanism of TNS.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Abrams P / 2002 / The standardisation of terminology of lower urinary tract function : report from the Standardisation Sub-committee of the International Continence Society / Neurourol Urodyn 21:167~178
Smith PP / 2016 / Detrusor underactivity and the underactive bladder: symptoms, function, cause-what do we mean? ICI-RS think tank 2014 / Neurourol Urodyn 35:312~317
van Kerrebroeck PE / 2007 / Results of sacral neuromodulation therapy for urinary voiding dysfunction: outcomes of a prospective, worldwide clinical study / J Urol 178:2029~2034
MacDiarmid SA / 2010 / Long-term durability of percutaneous tibial nerve stimulation for the treatment of overactive bladder / J Urol 183:234~240
Marchal C / 2011 / Percutaneous tibial nerve stimulation in treatment of overactive bladder : when should retreatment be started / Urology 78:1046~1050
Smith PP / 2016 / Detrusor underactivity and the underactive bladder: symptoms, function, cause-what do we mean? ICI-RS think tank 2014 / Neurourol Urodyn 35:312~317
van Kerrebroeck PE / 2007 / Results of sacral neuromodulation therapy for urinary voiding dysfunction: outcomes of a prospective, worldwide clinical study / J Urol 178:2029~2034
MacDiarmid SA / 2010 / Long-term durability of percutaneous tibial nerve stimulation for the treatment of overactive bladder / J Urol 183:234~240
Marchal C / 2011 / Percutaneous tibial nerve stimulation in treatment of overactive bladder : when should retreatment be started / Urology 78:1046~1050
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