지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 111 - 118 (8page)
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초록· 키워드
오류제보하기
Periodontitis and periimplantitis are caused as a result of dental biofilm formation. This biofilm is composed of multiple species of pathogens. Therefore, controlling biofilm formation is critical for disease prevention. To inhibit biofilm formation, sugars can be used to interrupt lectin-involving interactions between bacteria or between bacteria and a host. In this study, we evaluated the effect of D-Arabinose on biofilm formation of putative periodontal pathogens as well as the quorum sensing activity and whole protein profiles of the pathogens. Crystal violet staining, confocal laser scanning microscopy, and scanning electron microscopy revealed that D-Arabinose inhibited biofilm formation of Porphyromonas gingivalis , Fusobacterium nucleatum , and Tannerella forsythia . D-Arabinose also significantly inhibited the activity of autoinducer 2 of F. nucleatum and the expression of representative bacterial virulence genes.
Furthermore, D-Arabinose treatment altered the expression of some bacterial proteins. These results demonstrate that D-Arabinose can be used as an antibiofilm agent for the prevention of periodontal infections.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Daubert DM / 2019 / Biofilm as a risk factor in implant treatment / Periodontol 2000 81:29~40
de Melo F / 2020 / A systematic review of the microbiota composition in various periimplant conditions : data from 16S rRNA gene sequencing / Arch Oral Biol 117:104776
Griffen AL / 2012 / Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing / ISME J 6:1176~1185
Haffajee AD / 1994 / Microbial etiological agents of destructive periodontal diseases / Periodontol 2000 5:78~111
Hajishengallis G / 2021 / Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities / Nat Rev Immunol 21:426~440
de Melo F / 2020 / A systematic review of the microbiota composition in various periimplant conditions : data from 16S rRNA gene sequencing / Arch Oral Biol 117:104776
Griffen AL / 2012 / Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing / ISME J 6:1176~1185
Haffajee AD / 1994 / Microbial etiological agents of destructive periodontal diseases / Periodontol 2000 5:78~111
Hajishengallis G / 2021 / Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities / Nat Rev Immunol 21:426~440
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