지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제19권 제4호
- 발행연도
- 2021.11
- 수록면
- 705 - 711 (7page)
- DOI
- 10.9758/cpn.2021.19.4.705
이용수
초록· 키워드
오류제보하기
Objective: To study the efficiency and indication of combined medication with a stimulant and non-stimulant for attention- deficiency/hyperactivity disorder (ADHD), herein, the authors examined children and adult patients with ADHD.
Methods: Subjects included patients diagnosed with ADHD who paid two or more visits to the outpatient clinic of the Kyung Hee University hospital from January 2009 to December 2019. The authors examined the age, sex, drugs, treatment adherence, and reason for combined medication. The subjects were classified into four groups: treatment with a non-stimulant (atomoxetine) only (Group ATX), treatment with a stimulant (methylphenidate immediate-release, extended-release, or osmotic-release oral system) only (Group MPH), exposed to both but separately used (Group SEP), and exposed to both with combined use (Group COM). The patient was considered adherent to treatment (1) on visiting the hospital ten or more times or consecutively for six months, and (2) medication possession ratio ≥ 0.8.
Results: Of 929 patients, 229 (24.7%) were female. Group ATX comprised 146 (15.7%) patients, Group MPH comprised 627 (67.5%) patients, Group SEP comprised 106 (11.4%) patients, and Group COM comprised 50 (5.4%) patients.
Longer-term adherence was seen with combined medication and in females than with monopharmacy and in males.
The main indication for combination was dose-limiting untoward effects.
Conclusion: These results suggest that combined medication would facilitate treatment adherence for ADHD. Further research is essential for the replication of these results in a large sample and the investigation of the indications for administering combined medication in children and adults with ADHD.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Adler LA / 2006 / Combination pharmacotherapy for adult ADHD / Curr Psychiatry Rep 8:409~415
Toru Fujioka / 2016 / Advanced Test of Attention in Children with Attention-Deficit/Hyperactivity Disorder in Japan for Evaluation of Methylphenidate and Atomoxetine Effects / Clinical Psychopharmacology and Neuroscience 14(1):79~87
Greenhill LL / 1996 / Medication treatment strategies in the MTA Study : relevance to clinicians and researchers / J Am Acad Child Adolesc Psychiatry 35:1304~1313
Wagner KD / 2002 / Management of treatment refractory attentiondeficit/hyperactivity disorder in children and adolescents / Psychopharmacol Bull 36:130~142
Kooij JJS / 2013 / Adult ADHD: diagnostic assessment and treatment / Springer
Toru Fujioka / 2016 / Advanced Test of Attention in Children with Attention-Deficit/Hyperactivity Disorder in Japan for Evaluation of Methylphenidate and Atomoxetine Effects / Clinical Psychopharmacology and Neuroscience 14(1):79~87
Greenhill LL / 1996 / Medication treatment strategies in the MTA Study : relevance to clinicians and researchers / J Am Acad Child Adolesc Psychiatry 35:1304~1313
Wagner KD / 2002 / Management of treatment refractory attentiondeficit/hyperactivity disorder in children and adolescents / Psychopharmacol Bull 36:130~142
Kooij JJS / 2013 / Adult ADHD: diagnostic assessment and treatment / Springer
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