지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제14권 제4호
- 발행연도
- 2021.11
- 수록면
- 390 - 398 (9page)
- DOI
- https://doi.org/10.21053/ceo.2020.02250
이용수
초록· 키워드
오류제보하기
Objectives. Chronic rhinosinusitis with nasal polyps (CRSwNP) is a more severe inflammatory form of CRS that often coexists with obstructive sleep apnea (OSA). However, little is known about the relationship between OSA and the immune profile in patients with CRSwNP. We aimed to investigate the immune profile of patients with CRSwNP according to OSA severity.
Methods. This study included 63 patients with CRSwNP and nine control subjects. Protein levels of inflammatory mediators were determined using multiplex immunoassays. All patients underwent standard polysomnography.
Results. In patients with eosinophilic CRSwNP (ECRSwNP), interleukin (IL)-6 and chemokine [C-X-C motif] ligand (CXCL)-1 (type 1 immune-related markers) were upregulated in cases of moderate-to-severe OSA. Additionally, IL-4, IL-13, C-C motif chemokine (CCL)-11, CCL-24 (type 2 immune-related markers), and IL-17A (a type 3 immune-related marker) were present at elevated levels in patients with moderate-to-severe OSA. Although there were no significant differences in type 1, 2, or 3 immune-related markers among patients with non-eosinophilic CRSwNP (NECRSwNP) according to the severity of OSA, transforming growth factor-beta expression was higher in those with moderate-to-severe OSA. Furthermore, in ECRSwNP with moderate-to-severe OSA, associations were detected between serum markers and some upregulated inflammatory markers.
Conclusion. OSA may increase the heterogeneity of the immune profile (types 1, 2, and 3) in patients with ECRSwNP, but not in those with NECRSwNP.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Fokkens WJ / 2012 / EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists / Rhinology 50(1):1~12
Ohayon MM / 2002 / Epidemiology of insomnia: what we know and what we still need to learn / Sleep Med Rev 6(2):97~111
Bengtsson C / 2019 / Incident chronic rhinosinusitis is associated with impaired sleep quality: results of the RHINE study / J Clin Sleep Med 15(6):899~905
Stanley Yung Chuan Liu / 2020 / Surgical Algorithm for Obstructive Sleep Apnea: An Update / Clinical and Experimental Otorhinolaryngology 13(3):215~224
유명상 / 2020 / Maxillomandibular Advancement and Upper Airway Stimulation: Extrapharyngeal Surgery for Obstructive Sleep Apnea / Clinical and Experimental Otorhinolaryngology 13(3):225~233
Ohayon MM / 2002 / Epidemiology of insomnia: what we know and what we still need to learn / Sleep Med Rev 6(2):97~111
Bengtsson C / 2019 / Incident chronic rhinosinusitis is associated with impaired sleep quality: results of the RHINE study / J Clin Sleep Med 15(6):899~905
Stanley Yung Chuan Liu / 2020 / Surgical Algorithm for Obstructive Sleep Apnea: An Update / Clinical and Experimental Otorhinolaryngology 13(3):215~224
유명상 / 2020 / Maxillomandibular Advancement and Upper Airway Stimulation: Extrapharyngeal Surgery for Obstructive Sleep Apnea / Clinical and Experimental Otorhinolaryngology 13(3):225~233
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Is Obstructive Sleep Apnea a Risk Factor for Severe COVID-19?
sleep medicine research
2023 .06
-
성인 폐쇄성수면무호흡증이 대사증후군에 미치는 영향
Journal of Rhinology
2016 .01
-
폐쇄성 수면무호흡 환자의 주술기 관리
Journal of sleep medicine
2021 .01
-
Obstructive Sleep Apnea Screening Using a Piezo-Electric Sensor
Journal of Korean Medical Science
2017 .01
-
Obstructive Sleep Apnea and Medical Comorbidities in the Asian Population: Evidence From a Nationwide Healthcare System Data in South Korea
PSYCHIATRY INVESTIGATION
2024 .09
-
렘수면 관련 폐쇄성 수면무호흡 환자들에서 기도양압기 치료의 순응도와 효과분석
대한이비인후-두경부외과학회지
2024 .08
-
소아 수면무호흡에서 상기도의 역할
Allergy Asthma & Respiratory Diseases
2017 .01
-
The Influence of Obesity on the Association of Obstructive Sleep Apnea and Atrial Fibrillation
sleep medicine research
2021 .01
-
Obstructive Sleep Apnea in Patients with Branch Retinal Vein Occlusion: A Preliminary Study
Korean Journal of Ophthalmology
2016 .01
-
Development, Validation and Comparison of Artificial Neural Network and Logistic Regression Models Predicting Eosinophilic Chronic Rhinosinusitis With Nasal Polyps
Allergy, Asthma & Immunology Research
2023 .01
-
Differential Effects of Obesity on Obstructive Sleep Apnea Syndrome according to Age
PSYCHIATRY INVESTIGATION
2017 .01
-
수면호흡장애 진단과 치료의 최신 지견- 폐쇄성 수면무호흡증을 중심으로
신경정신의학
2020 .01
-
폐쇄성수면무호흡증의 표현형에 따른 구강내장치치료의 장기 유효성
대한치과의사협회지
2022 .09
-
폐쇄성수면무호흡증(Obstructive Sleep Apnea)의 치료에 대한 치과의사의 임상적 접근
대한치과의사협회지
2015 .01
-
Comparison of Anthropometric Data Between Asian and Caucasian Patients With Obstructive Sleep Apnea: A Meta-Analysis
Clinical and Experimental Otorhinolaryngology
2016 .01
-
한국 아동의 비타민 D 수치와 폐쇄성 수면 무호흡증 사이의 상관 관계
임상이비인후과
2021 .12
-
한국 중장년층의 구강 건강 상태가 폐쇄성 수면 무호흡증 위험인자에 미치는 영향: 국민건강영양조사를 바탕으로(2019년도)
한국치위생학회지
2022 .08
-
수면호흡장애의 진단과 수면다원검사
대한치과의사협회지
2015 .04
-
Metabolic Consequences of Obstructive Sleep Apnea Especially Pertaining to Diabetes Mellitus and Insulin Sensitivity
Diabetes and Metabolism Journal
2019 .01
-
Adherence to Positive Airway Pressure therapy as Severity of Adult Obstructive Sleep Apnea
대한이비인후-두경부외과학회지
2022 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0