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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 258 - 267 (10page)
- DOI
- 10.5230/jgc.2021.21.e25
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초록· 키워드
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Purpose: As the rate of endoscopic resection for early gastric cancer (EGC) has increased in patients with comorbid diseases, it is necessary to elucidate the efficacy of endoscopic submucosal dissection (ESD) for EGC in patients with comorbidities. This study aimed to analyze the clinical outcomes of ESD for EGC in patients with comorbidities.
Materials and Methods: A total of 969 patients with 1,015 lesions who underwent ESD for EGC at Seoul National University Hospital between 2010 and 2014 were analyzed. The shortand long-term clinical outcomes were evaluated according to the comorbidity status.
Results: Comorbidities were observed in 558 patients (57.6%). The comorbidity group had a higher proportion of patients using antithrombotic agents (29.5% vs. 0.9%; P<0.0001).
Although procedure-related complications (bleeding and perforation) were not significantly different between the two groups, the length of hospital stay was significantly longer (1.8 vs.
1.4 days, P=0.023), while survival was significantly shorter in the comorbidity group (5-year overall survival rate: 90.5% vs. 97.2%, P<0.0001; 5-year disease-specific survival rate: 97.9% vs. 100%, P=0.018; 5-year disease-free survival rate: 83.4% vs. 89.2%, P=0.007).
Conclusions: Gastric ESD can be performed in patients with comorbidities without increasing the risk of complications.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Bray F / 2018 / Global cancer statistics 2018 : GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries / CA Cancer J Clin 68:394~424
홍세리 / 2020 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2017 / Cancer Research and Treatment 52(2):335~350
김윤경 / 2014 / Effects of Screening on Gastric Cancer Management: Comparative Analysis of the Results in 2006 and in 2011 / Journal of Gastric Cancer 14(2):129~134
Guideline Committee of the Korean Gastric Cancer Association / 2019 / Korean Practice Guideline for Gastric Cancer 2018; Evidence-based, Multi-disciplinary Approach / Journal of Gastric Cancer 19(1):1~48
Il Ju Choi / 2016 / Short-Term Outcomes of Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer: A Prospective Multicenter Cohort Study / Gut and Liver 10(5):739~748
홍세리 / 2020 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2017 / Cancer Research and Treatment 52(2):335~350
김윤경 / 2014 / Effects of Screening on Gastric Cancer Management: Comparative Analysis of the Results in 2006 and in 2011 / Journal of Gastric Cancer 14(2):129~134
Guideline Committee of the Korean Gastric Cancer Association / 2019 / Korean Practice Guideline for Gastric Cancer 2018; Evidence-based, Multi-disciplinary Approach / Journal of Gastric Cancer 19(1):1~48
Il Ju Choi / 2016 / Short-Term Outcomes of Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer: A Prospective Multicenter Cohort Study / Gut and Liver 10(5):739~748
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