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논문 기본 정보

자료유형
학술저널
저자정보
Carlota Blanco (Periodontology Unit Faculty of Odontology University of Santiago de Compostela & Medical-Surgic) Antonio Liñares (Periodontology Unit Faculty of Odontology University of Santiago de Compostela & Medical-Surgic) Jose Dopico (Periodontology Unit Faculty of Odontology University of Santiago de Compostela & Medical-Surgic) Alex Pico (Periodontology Unit Faculty of Odontology University of Santiago de Compostela & Medical-Surgic) Tomás Sobrino (Clinical Neurosciences Research Laboratory Health Research Institute of Santiago de Compostela) Yago Leira (Clinical Neurosciences Research Laboratory Health Research Institute of Santiago de Compostela) Juan Blanco (Periodontology Unit Faculty of Odontology University of Santiago de Compostela & Medical-Surgic)
저널정보
대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제51권 제5호
발행연도
2021.10
수록면
342 - 351 (10page)
DOI
10.5051/jpis.2100920046

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Purpose: The aim of this study was to compare the inflammatory and lipid profile of patients with and without peri-implantitis. Methods: A cross-sectional biochemical study was carried out in which blood samples were collected from 16 patients with peri-implantitis and from 31 subjects with healthy implants. Clinical peri-implant parameters were obtained from all subjects. Levels of tumor necrosis factor-alpha and interleukin-10 (IL-10) were measured in serum. Lipid fractions, glucose and creatinine levels, and complete blood count were also assessed. Results: After controlling for a history of periodontitis, statistically significant differences between peri-implantitis patients and controls were found for total cholesterol (estimated adjusted mean difference, 76.4 mg/dL; 95% confidence interval [CI], 39.6, 113.2 mg/dL; P<0.001), low-density lipoprotein (LDL) cholesterol (estimated adjusted mean difference, 57.7 mg/dL; 95% CI, 23.8, 91.6 mg/dL; P<0.001), white blood cells (WBC) (estimated adjusted mean difference, 2.8×103/μL; 95% CI, 1.6, 4.0×103/μL; P<0.001) and IL-10 (estimated adjusted mean difference, ?10.4 pg/mL; 95% CI, ?15.8, ?5.0 pg/mL; P<0.001). The peri-implant probing pocket depth (PPD) was modestly positively correlated with total cholesterol (r=0.512; P<0.001), LDL cholesterol (r=0.463; P=0.001), and WBC (r=0.519; P<0.001). A moderate negative correlation was observed between IL-10 and PPD (r=0.609; P<0.001). Conclusions: Otherwise healthy individuals with peri-implantitis showed increased low-grade systemic inflammation and dyslipidemia.

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