지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.8
- 수록면
- 88 - 99 (12page)
- DOI
- 10.13078/jsm.210007
이용수
초록· 키워드
오류제보하기
Objectives: This study aimed to investigate the prevalence, incidence, and real-world diagnostic and treatment patterns, healthcare resource utilization (HCRU), and associated costs of narcolepsy in Germany.
Methods: This study was based on German claims data (2013?2018). Any patient with at least two outpatient specialist diagnoses and/or one inpatient diagnosis of narcolepsy was eligible for inclusion. Three cohorts were specified: 1) narcolepsy-prevalent patients alive on July 1, 2017; 2) narcolepsy-incident patients; and 3) newly treated patients. Descriptive analyses of the outcome measures were conducted. Results: We identified 133 prevalent narcolepsy patients (mean age: 46.2 years, 36.3% female), 71 incident patients, and 41 treatment starters. The prevalence of narcolepsy was 3.1?9.1 per 100,000 persons within the German population; the cumulative incidence between July 1, 2017, and June 30, 2018, was 0.83/100,000 persons.
Among the incident patients, 62.0% underwent at least one predefined diagnostic procedure. Modafinil was the most prescribed medication for the treatment starters (46.3%) and prevalent patients (24.1%), but 59.4% of the prevalent patients did not receive any narcolepsy-specific pharmacological treatment. Prevalent patients with narcolepsy consulted physicians significantly more often than a healthy matched control group and experienced more all-cause hospitalizations. The mean total direct healthcare costs were higher for narcolepsy patients by €2,429 per patient-year. Conclusions: Not all narcolepsy patients undergo appropriate diagnostic procedures or narcolepsy-specific medications, as indicated by the treatment guidelines.
More emphasis on the optimization of the management of this disease is needed, given its high prevalence and associated economic burden.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
G. Mayer / 2014 / Narkolepsie / Der Nervenarzt 85(1):26~34
Lois E. Krahn / 2005 / Characterizing the Emotions That Trigger Cataplexy / The Journal of Neuropsychiatry and Clinical Neurosciences 17(1):45~50
Mayer G / 2002 / The implications of gender and age at onset of first symptoms in narcoleptic patients in Germany—results from retrospective evaluation of hospital records / Somnologie 6(1):13~18
Natalia M. Flores / 2016 / The Humanistic and Economic Burden of Narcolepsy / Journal of Clinical Sleep Medicine 12(03):401~407
FRANCESCA INGRAVALLO / 2008 / Medico-legal assessment of disability in narcolepsy: an interobserver reliability study / Journal of Sleep Research 17(1):111~119
Lois E. Krahn / 2005 / Characterizing the Emotions That Trigger Cataplexy / The Journal of Neuropsychiatry and Clinical Neurosciences 17(1):45~50
Mayer G / 2002 / The implications of gender and age at onset of first symptoms in narcoleptic patients in Germany—results from retrospective evaluation of hospital records / Somnologie 6(1):13~18
Natalia M. Flores / 2016 / The Humanistic and Economic Burden of Narcolepsy / Journal of Clinical Sleep Medicine 12(03):401~407
FRANCESCA INGRAVALLO / 2008 / Medico-legal assessment of disability in narcolepsy: an interobserver reliability study / Journal of Sleep Research 17(1):111~119
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
National Estimates of Narcolepsy in Korea
Journal of Clinical Neurology
2023 .01
-
Exploring the Intersection of Narcolepsy and Attention Deficit Hyperactivity Disorder: Similarities, Differences, and Clinical Implications
sleep medicine research
2024 .03
-
Clinical Characteristics, Comorbidities, and Quality of Life in Korean Patients With Narcolepsy: Findings From an Online Survey
Journal of sleep medicine
2024 .08
-
Spectral Analysis of Polysomnography in Narcolepsy
PSYCHIATRY INVESTIGATION
2017 .01
-
사건수면으로 발견된 기면병
Journal of sleep medicine
2018 .01
-
기면병 및 과다수면 진단과 치료의 최신 지견
신경정신의학
2020 .01
-
Clinical and Polysomnographic Characteristics of Childhood Narcolepsy in Korea
대한소아신경학회지
2016 .09
-
Pathological Gambling Disorder Associated With Modafinil Therapy in a Patient With Type 1 Narcolepsy
Journal of sleep medicine
2023 .04
-
Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia
sleep medicine research
2023 .03
-
Comorbidity of Narcolepsy and Obstructive Sleep Apnea: A Case Report
sleep medicine research
2018 .01
-
Incidence of narcolepsy symptoms after taking COVID-19 vaccines: a Jordanian cross-sectional study
Clinical and Experimental Vaccine Research
2024 .07
-
기면병 환자에서 다중수면잠복기검사의 검사-재검사 신뢰도 검증
Journal of sleep medicine
2020 .01
-
Two Cases of Narcoleptic patients with sleep paralysis as a Chief Complaint
sleep medicine research
2018 .01
-
Fecal microbiota analysis of obese dogs with underlying diseases: a pilot study
Korean Journal of Veterinary Research(대한수의학회지)
2015 .09
-
Central Neurocytoma Presenting as Symptomatic Cataplexy
Journal of sleep medicine
2020 .01
-
Pituitary Macrotumor Causing Narcolepsy-cataplexy in a Dachshund 〈닥스훈트에서의 뇌하수체 거대종양으로 인한 기면증- 급발작 증상〉S.schmid, A.Hodshon, S.Olin, I.Psfeiffer, and S. Hecht
WITH CAP(COMPANION ANIMAL PRACTICE)
2020 .11
-
Sufficient explanation of management affects patient satisfaction and the practice of post-treatment management in spinal pain, a multicenter study of 1007 patients
The Korean Journal of Pain
2017 .01
-
An Exploration Into Patients’ Experiences That Make Them Feel Safe During Hospitalization: A Qualitative Study
Journal of Korean Medical Science
2022 .08
-
19세 미만 인구의 정신장애 진단 분포 : 국민건강보험 자료를 중심으로
소아청소년정신의학
2016 .06
-
Primary malignant mucosal melanoma of the maxillofacial area
대한구강악안면외과학회지
2021 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0