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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충북대학교 동물의학연구소 Journal of Biomedical and Translational Research Journal of Biomedical and Translational Research 제22권 제3호
- 발행연도
- 2021.9
- 수록면
- 105 - 110 (6page)
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C-reactive protein (CRP) is an acute-phase protein produced by hepatocytes. The plasma concentration of CRP peaks around 48 hours following stimulation. A rapid decrease in CRP levels is observed when the stimuli end. Considering these characteristics of CRP, it is used to evaluate acute inflammatory responses in clinics. In addition, as it reflects the degree of surgical trauma, measuring the CRP concentration is an effective method of evaluating tis sue damage depending upon the surgical method. As CRP is also an acute-phase protein in dogs, the purpose of the present study was to compare the factors related to acute inflam matory responses between dogs undergoing elective general surgery (GS) and orthopedic surgery (OS). A total of 44 healthy dogs were included in this study. The sex ratio of dogs that underwent OS was similar. Both groups showed increased CRP levels and white blood cell (WBC) counts on post-operative day (POD) 1-2. The CRP level in the OS group on POD 1-2 was significantly higher than that of the GS group and it was increased about 16-fold compared to the pre-operative value. No significant difference in WBC counts was observed between the two groups. Although a slight increase in the WBC count was observed on POD 1-2 in both groups, it was near the reference range during follow-up. Thus, measuring CRP levels can be more effective in evaluating acute inflammatory responses than WBC counts.
Although a high level of post-operative serum CRP concentrations was observed in the OS group, it rapidly decreased to a level similar to the pre-operative value if there were no post-operative complications.
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참고문헌 (25)
참고문헌 신청
Young B / 1991 / C-reactive protein : a critical review / Pathology 23:118~124
Muñoz JL / 2018 / Procalcitonin and C-reactive protein as early markers of anastomotic leak after laparoscopic colorectal surgery within an enhanced recovery after surgery(ERAS)program / Surg Endosc 32:4003~4010
Pepys MB / 2003 / C-reactive protein : a critical update / J Clin Invest 111:1805~1812
Watt DG / 2015 / Routine clinical markers of the magnitude of the systemic inflammatory response after elective operation : a systematic review / Surgery 157:362~380
Huang TJ / 2005 / Less systemic cytokine response in patients following microendoscopic versus open lumbar discectomy / J Orthop Res 23:406~411
Muñoz JL / 2018 / Procalcitonin and C-reactive protein as early markers of anastomotic leak after laparoscopic colorectal surgery within an enhanced recovery after surgery(ERAS)program / Surg Endosc 32:4003~4010
Pepys MB / 2003 / C-reactive protein : a critical update / J Clin Invest 111:1805~1812
Watt DG / 2015 / Routine clinical markers of the magnitude of the systemic inflammatory response after elective operation : a systematic review / Surgery 157:362~380
Huang TJ / 2005 / Less systemic cytokine response in patients following microendoscopic versus open lumbar discectomy / J Orthop Res 23:406~411
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