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논문 기본 정보

자료유형
학술저널
저자정보
Kojima Tsukasa (Division of Radiology Department of Medical Technology Kyushu University Hospital Fukuoka Japan.) Yamasaki Yuzo (Department of Molecular Imaging) Kamitani Takeshi (Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University Fukuoka Japa) Yabuuchi Hidetake (Department of Health Sciences Graduate School of Medical Sciences Kyushu University Fukuoka Japan.) Shirasaka Takashi (Division of Radiology Department of Medical Technology Kyushu University Hospital Fukuoka Japan.) Shimomiya Yamato (Department of Clinical Application Ziosoft Inc. Tokyo Japan.) Kondo Masatoshi (Division of Radiology Department of Medical Technology Kyushu University Hospital Fukuoka Japan.) Hamasaki Hiroshi (Division of Radiology Department of Medical Technology Kyushu University Hospital Fukuoka Japan.) Kato Toyoyuki (Division of Radiology Department of Medical Technology Kyushu University Hospital Fukuoka Japan.) Nagao Michinobu (Department of Diagnostic Imaging and Nuclear Medicine Tokyo Women's Medical University Tokyo Japan.) Honda Hiroshi (Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University Fukuoka Japa)
저널정보
아시아심장혈관영상의학회 Cardiovascular Imaging Asia Cardiovascular Imaging Asia Vol.3 No.1
발행연도
2019.1
수록면
1 - 7 (7page)
DOI
10.22468/cvia.2018.00213

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Objective: The smallest diagnostically sufficient amount of contrast media (CM) should be used for coronary computed tomography angiography (CCTA) to minimize the risk of contrast- induced nephrotoxicity in elderly patients with coronary artery disease. The purpose of this study was to propose dynamic-CCTA using a low dose of CM and temporal maximum intensity projection (TMIP) and to investigate its image quality compared to standard-CCTA. Materials and Methods: Participants comprised 30 patients with coronary artery disease who underwent dynamic-CCTA and standard-CCTA using 320-row CT. Dynamic-CCTA was continuously performed at mid-diastole throughout 15?25 cardiac cycles after bolus injection of CM [103 mg iodine/kg body weight (mgI/kg)]. TMIP-CCTA was reconstructed from three-phase dynamic-CCTA data, including a phase with peak enhancement of the ascending aorta. Standard-CCTA was performed using a standard CM dose (259 mgI/kg). Image quality of both TMIP-CCTA and standard-CCTA was analyzed. Results: The amount of CM used in TMIP-CCTA and standard-CCTA was 16.2±2.6 mL and 40.1±7.3 mL, respectively. The mean effective radiation dose was not significantly different between the two methods. Mean coronary attenuation was significantly lower for TMIP-CCTA than standard-CCTA [346.9±82.8 Hounsfield units (HU) vs. 455.4±75.3 HU, p<0.05]. Image noise was significantly lower for TMIP-CCTA than standard-CCTA (20.0±3.2 HU vs. 28.1± 3.6 HU, p<0.05). There were no differences in signal-to-noise ratio and visual assessment scores between the two methods. Conclusion: TMIP-CCTA can be performed using more than 50% less CM with the same image quality as standard-CCTA.

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