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자료유형
학술저널
저자정보
Elie Massaad (Department of Neurosurgery Massachusetts General Hospital Harvard Medical School) Muhamed Hadzipasic (Department of Neurosurgery Massachusetts General Hospital Harvard Medical School) Ali Kiapour (Department of Neurosurgery Massachusetts General Hospital Harvard Medical School) Asad M. Lak (Harvard Medical School) Ganesh Shankar (Department of Neurosurgery Massachusetts General Hospital Harvard Medical School) Hasan A. Zaidi (Harvard Medical School) Stuart H. Hershman (Department of Orthopedic Surgery Massachusetts General Hospital Harvard Medical School) John H. Shin (Department of Neurosurgery Massachusetts General Hospital Harvard Medical School)
저널정보
대한척추신경외과학회 Neurospine Neurospine 제18권 제3호
발행연도
2021.9
수록면
533 - 542 (10page)
DOI
10.14245/ns.2040656.328

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Objective: Adult cervical deformity (ACD) is a debilitating spinal condition that causes significant pain, neurologic dysfunction, and functional impairment. Surgery is often performed to correct cervical alignment, but the optimal amount of correction required to improve patient-reported outcomes (PROs) are not yet well-defined. Methods: A review of the literature was performed and Fisher z-transformation (Zr) was used to pool the correlation coefficients between alignment parameters and PROs. The strength of correlation was defined according to the following: poor (0<r≤0.3), fair (0.3<r≤0.5), moderate (0.5<r≤0.8), and strong (0.8<r≤1). Results: Increased C2?7 sagittal vertical axis was fairly associated with increased Neck Disability Index (NDI) (pooled Zr=0.31; 95% confidence interval [CI], -0.03 to 0.58). Changes in T1 slope minus cervical lordosis poorly correlated with NDI (pooled Zr=-0.04; 95% CI, -0.23 to 0.30). Increased C7?S1 was poorly associated with worse EuroQoL 5-Dimension (pooled Zr=-0.22; 95% CI, -0.36 to -0.06). Correction of horizontal gaze did not correlate with legacy metrics. Modified Japanese Orthopedic Association correlated with C2-slope, C7?S1, and C2?S1. Conclusion: Spinal alignment parameters variably correlated with improved health-related quality of life and myelopathy after corrective surgery for ACD. Further studies evaluating legacy PROs, Patient-Reported Outcomes Measurement System, and ACD specific instruments are needed for further validation.

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