Impact of prone position on outcomes of COVID-19 patients with spontaneous breathing

Mabrouk Bahloul; Sana Kharrat; Malek Hafdhi; Anis Maalla; Olfa Turki; Kamilia Chtara; Rania Ammar; Basma Suissi; Chokri Ben Hamida; Hedi Chelly; Khaiereddine Ben Mahfoudh; Mounir Bouaziz

doi:10.4266/acc.2021.00500

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자료유형: 학술저널

저자정보: Mabrouk Bahloul (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Sana Kharrat (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Malek Hafdhi (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Anis Maalla (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Olfa Turki (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Kamilia Chtara (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Rania Ammar (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Basma Suissi (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Chokri Ben Hamida (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Hedi Chelly (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Khaiereddine Ben Mahfoudh (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia) Mounir Bouaziz (Habib Bourguiba University Hospital and Sfax University Sfax Tunisia)

저널정보: 대한중환자의학회 Acute and Critical Care Acute and Critical Care 제36권 제3호

발행연도: 2021.8

수록면: 208 - 214 (7page)

DOI: 10.4266/acc.2021.00500

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Background: In this study, we explored whether early application of the prone position (PP) can improve severe hypoxemia and respiratory failure in coronavirus disease 2019 (COVID-19) patients with spontaneous breathing. Methods: This is a prospective observational study of severe, critically ill adult COVID-19 pa tients admitted to the intensive care unit. All vital parameters were recorded in real time for all patients. Moreover, the results of chest computed tomography (CT), when available, were analyzed. Results: PP was applied in 21 patients who were breathing spontaneously. The application of PP was associated with a significant increase in oxygen saturation measured by pulse oxime try (SpO2) from 82%±12% to 96%±3% (P<0.001) 1 hour later. Moreover, PP was associated with a significant reduction in respiratory rate from 31±10 to 21±4 breaths/min (P<0.001). Furthermore, the number of patients who exhibited signs of respiratory distress after PP was reduced from 10 (47%) to 3 (14%) (P=0.04). Early PP application also led to a clear improve ment on CT imaging. It was not, however, associated with a reduction in mortality rate or in the use of invasive mechanical ventilation (P>0.05 for both). Conclusions: Our study confirmed that the early application of PP can improve hypoxemia and tachypnea in COVID-19 patients with spontaneous breathing. Randomized controlled tri als are needed to confirm the beneficial effects of PP in COVID-19 patients with spontaneous breathing.

#COVID-19 #intensive care unit #patient outcomes #prone position #respiratory distress

참고문헌 (1)

참고문헌 신청

Mallikarjuna Ponnapa Reddy / 2021 / Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis / Critical Care Medicine 49(10):e1001~e1014

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