지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.6
- 수록면
- 110 - 120 (11page)
- DOI
- 10.1186/s40824-016-0063-5
이용수
초록· 키워드
오류제보하기
Background: We investigated the physicochemical properties of Medifoam® N and its wound healing performance compared to other commercially available polyurethane (PU) foam dressing in vitro and in vivo to gain insight in their clinical performance. Methods: Wound contact layer and cross-section of eleven polyurethane foam dressings were assessed with field-emission scanning electron microscope. Thickness, density, tensile strength, elongation, moisture-vapor transmission rate (MVTR), retention and absorptivity were measured to compare physical properties. Phosphate-buffered saline (PBS) solution absorption patterns were compared. An animal model for wound-healing was applied to validate in vitro findings. Results: Among eleven tested foam dressings, Medifoam® N has the smallest pore and cell sizes with excellent uniformity, i.e. it has 25 ~ 75 μm on the wound contact layer and 100 ~ 350 μm in the cross-section while other dressings have a larger pose size with larger variability. Compared to other PU foams, Medifoam® N also has moderate thickness, density, tensile strength, elongation and MVTR. Furthermore, it has excellent fluid absorption and retention capacity. These intrinsic properties of Medifoam® N contributed to improve fluid absorption patterns, i.e. other dressing material flawed out PBS solution on the dressings while Medifoam® N retained all the tested solutions. In animal wound-healing study, Medifoam® N treated animals showed excellent angiogenesis and collagen deposition even though epithelial recovery rate was not significantly different to other dressings. Conclusions: Medifoam® N has optimized physical properties and thus improved fluid absorption/retention capacity. Compared to other dressings, Medifoam® N showed excellent fluid absorption patterns and these characteristics contributed to improved wound healing and excellent angiogenic potential. We found that Medifoam® N showed the best results among the employed dressing samples.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Moore OA / 2001 / Systematic review of the use of honey as a wound dressing / BMC Complement Altern Med 1:2
Shobana S / 2013 / Finger millet (Ragi, Eleusine coracana L.): a review of its nutritional properties, processing, and plausible health benefits / Adv Food Nutr Res 69:1~39
Beam JW / 2009 / Topical silver for infected wounds / J Athl Train 44:531~533
Zahedi P / 2010 / A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages / Polym Adv Technol 21:77~95
Khan TA / 2000 / Mechanical, bioadhesive strength and biological evaluations of chitosan films for wound dressing / J Pharm Pharmaceutical Sci 3:303~311
Shobana S / 2013 / Finger millet (Ragi, Eleusine coracana L.): a review of its nutritional properties, processing, and plausible health benefits / Adv Food Nutr Res 69:1~39
Beam JW / 2009 / Topical silver for infected wounds / J Athl Train 44:531~533
Zahedi P / 2010 / A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages / Polym Adv Technol 21:77~95
Khan TA / 2000 / Mechanical, bioadhesive strength and biological evaluations of chitosan films for wound dressing / J Pharm Pharmaceutical Sci 3:303~311
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