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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 275 - 281 (7page)
- DOI
- 10.1186/s40824-016-0073-3
이용수
초록· 키워드
오류제보하기
Background: Hyaluronic acid (HA) dermal biphasic fillers are synthesized for their efficacy in correcting aesthetic defects such as wrinkles, scars and facial contouring defects. The fillers consist of crosslinked HA microspheres suspended in a noncrosslinked HA. To extend the duration of HAs within the dermis and obtain the particle texturing feel, HAs are crosslinked to obtain the suitable mechanical properties. Results: Hyaluronic acid (HA) dermal biphasic fillers are prepared by mixing the crosslinked HA microspheres and the noncrosslinked HAs. The elastic modulus of the fillers increased with raising the volume fraction of the microspheres. The mechanical properties and the particle texturing feel of the fillers made from crosslinked HA (1058 kDa) microspheres suspended in noncrosslinked HA (1368 kDa) are successfully achieved, which are adequate for the fillers. Conclusions: Dermal biphasic HA fillers made from 1058 kDa exhibit suitable elastic moduli (211 to 420 Pa) and particle texturing feel (scale 7 ~ 9).
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Schante CE / 2011 / Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications / Carbohydr Polym 85:469~489
Gatta AL / 2011 / Comparative analysis of commercial deraml fillers based on crosslinked hyaluronan : physical characterization and in vitro enzymatic degradation / Polym Degrad Stab 96:630~636
Park KY / 2014 / Comparative study of hyaluronic acid fillers by in vitro and in vivo testing / J Euro Acad Dermatol Venereol 28:565~568
Flynn TC / 2011 / Comparative histology of intradermal implantation of mono and biphasic hyaluronic acid fillers / Dermatol Surg 37:637~643
Redbord KP / 2011 / Soft-tissue augmentation with hyaluronica acid and calcium hydroxyl apatite fillers / Dermatol Ther 24:71~81
Gatta AL / 2011 / Comparative analysis of commercial deraml fillers based on crosslinked hyaluronan : physical characterization and in vitro enzymatic degradation / Polym Degrad Stab 96:630~636
Park KY / 2014 / Comparative study of hyaluronic acid fillers by in vitro and in vivo testing / J Euro Acad Dermatol Venereol 28:565~568
Flynn TC / 2011 / Comparative histology of intradermal implantation of mono and biphasic hyaluronic acid fillers / Dermatol Surg 37:637~643
Redbord KP / 2011 / Soft-tissue augmentation with hyaluronica acid and calcium hydroxyl apatite fillers / Dermatol Ther 24:71~81
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