지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.6
- 수록면
- 47 - 49 (3page)
- DOI
- https://doi.org/10.12701/yujm.2015.32.1.47
이용수
초록· 키워드
오류제보하기
Sorafenib is indicated for the treatment of advanced hepatocellular carcinoma (HCC), but although rare, tumor lysis syndrome (TLS) can be fatal in HCC patients with a large tumor burden. The authors describe the case of a 55-year-old hepatitis B carrier who visited our clinic with progressive dyspnea for 3 weeks. Chest and abdominal computed tomography revealed a huge HCC in the left lobe of the liver with invasion of the inferior vena cava, right atrium, and pulmonary arteries. After 8 days of sorafenib administration, TLS was diagnosed based on the characteristic findings of hyperuricemia, hyperkalemia, and acute kidney injury with massive tumor necrosis by follow-up imaging. Despite discontinuation of sorafenib and supportive care, the patient’s clinical course rapidly deteriorated. The authors describe a rare but fatal complication that occurred soon after sorafenib initiation for HCC. Careful follow-up is required after commencing sorafenib therapy for the early diagnosis and management of TLS.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Cairo MS / 2010 / Recommendations for the evaluation of risk and prophylaxis of tumour lysis syndrome (TLS) in adults and children with malignant diseases: an expert TLS panel consensus / Br J Haematol 149:578~586
Howard SC / 2011 / The tumor lysis syndrome / N Engl J Med 364:1844~1854
Llovet JM / 2008 / Sorafenib in advanced hepatocellular carcinoma / N Engl J Med 359:378~390
Hsieh PM / 2009 / Tumor lysis syndrome after transarterial chemoembolization of hepatocellular carcinoma:case reports and literature review / World J Gastroenterol 15:4726~4728
Lehner SG / 2005 / Tumor lysis syndrome after radiofrequency ablation of hepatocellular carcinoma / AJR Am J Roentgenol 185:1307~1309
Howard SC / 2011 / The tumor lysis syndrome / N Engl J Med 364:1844~1854
Llovet JM / 2008 / Sorafenib in advanced hepatocellular carcinoma / N Engl J Med 359:378~390
Hsieh PM / 2009 / Tumor lysis syndrome after transarterial chemoembolization of hepatocellular carcinoma:case reports and literature review / World J Gastroenterol 15:4726~4728
Lehner SG / 2005 / Tumor lysis syndrome after radiofrequency ablation of hepatocellular carcinoma / AJR Am J Roentgenol 185:1307~1309
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Tumor lysis syndrome following sorafenib treatment in hepatocellular carcinoma
영남의대학술지
2015 .01
-
Low dose steroid-induced tumor lysis syndrome in a hepatocellular carcinoma patient
Clinical and Molecular Hepatology
2015 .01
-
Advances in Management of Hepatocellular Carcinoma
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Complete response of advanced hepatocellular carcinoma to sorafenib : another case and a comprehensive review
Clinical and Molecular Hepatology
2017 .01
-
Long-term Survival of a Patient with a Large Hepatocellular Carcinoma with Main Portal Vein Tumor Thrombosis and Spontaneous Tumor Rupture
Journal of Liver Cancer
2020 .01
-
Spontaneous Tumor Lysis Syndrome Presenting Acute Kidney Injury with Extreme Hyperuricemia and Urinary Stone: A Rare Case of Spontaneous Tumor Lysis Syndrome
Childhood Kidney Diseases
2017 .01
-
Long-term outcomes of patients with advanced hepatocellular carcinoma who achieved complete remission after sorafenib therapy
Clinical and Molecular Hepatology
2015 .01
-
간세포암의 진단과 치료에서 종양표지자의 역할
대한내과학회지
2020 .02
-
Growth rate of early-stage hepatocellular carcinoma in patients with chronic liver disease
Clinical and Molecular Hepatology
2015 .01
-
Current Trends and Recent Advances in Diagnosis, Therapy, and Prevention of Hepatocellular Carcinoma
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Tumor-Associated Macrophages in Hepatocellular Carcinoma: Friend or Foe?
Gut and Liver
2021 .01
-
Real-Life Experience of Sorafenib Treatment for Hepatocellular Carcinoma in Korea: From GIDEON Data
Cancer Research and Treatment
2016 .01
-
Role of Surgery in Stage IV Hepatocellular Carcinoma (HCC)
대한임상종양학회 학술대회지
2015 .02
-
Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors
Journal of Liver Cancer
2020 .01
-
A case report of advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy and sorafenib combination therapy followed by metastasectomy of lung and muscle metastases
Journal of Liver Cancer
2022 .03
-
Discrepancy between the Actual Clinical Status of Patients with Hepatocellular Carcinoma and Expectations from Hepatocellular Carcinoma Surveillance: a Single-Center Study
Journal of Liver Cancer
2019 .01
-
Liver Transplantation in Mixed Hepatocellular Carcinoma and Cholangiocarcinoma
Journal of Liver Cancer
2019 .01
-
The Genomic Landscape and Its Clinical Implications in Hepatocellular Carcinoma
Journal of Liver Cancer
2019 .01
-
Hepatocellular carcinoma surveillance in the 21st century: Saving lives or causing harm?
Clinical and Molecular Hepatology
2019 .01
-
A clinical and pathological update on hepatocellular carcinoma
Journal of Liver Cancer
2022 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0