지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 92 - 99 (8page)
- DOI
- https://doi.org/10.14449/jbd.2016.4.2.92
이용수
초록· 키워드
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Purpose: This study aimed to evaluate the usefulness of the axillary lymph node to primary breast tumor maximum standardized uptake value (SUVmax) ratio in 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for predicting the presence of metastasis in axillary lymph nodes. Methods: Herein, 196 consecutive patients with breast cancer who underwent PET/CT before surgery from January 2009 to January 2013 were included. We calculated the axillary lymph node to primary breast tumor SUVmax ratio using PET/CT. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the ratio were compared with those of nodal SUVmax and axillary ultrasonography. Axillary node metastasis was confirmed with sentinel node biopsy or axillary dissection. Results: The SUVmax ratio (cutoff, 0.14; area under the curve, 0.741) had 55.4% sensitivity, 91.6% specificity, 76.6% PPV, and 80.5% NPV for predicting axillary node metastasis. No significant difference was observed in terms of predicting axillary node metastasis among the SUVmax ratio, nodal SUVmax, and ultrasonography. In the multivariate analysis, primary tumor size (p=0.014), SUVmax of the primary tumor (p=0.011), axillary ultrasonography findings, nodal SUVmax, and SUVmax ratio were significantly associated with lymph node metastasis (p<0.001). Conclusion: The axillary lymph node to primary breast tumor SUVmax ratio predicted axillary lymph node metastasis, although no significant difference in diagnostic performance was observed between PET/CT and ultrasonography. The axillary lymph node to primary breast tumor SUVmax ratio may be considered an additional method for the preoperative evaluation of axillary lymph node status.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Jemal A / 2008 / Cancer statistics, 2008 / CA Cancer J Clin 58:71~96
Chua B / 2001 / Frequency and predictors of axillary lymph node metastases in invasive breast cancer / ANZ J Surg 71:723~728
Ivens D / 1992 / Assessment of morbidity from complete axillary dissection / Br J Cancer 66:136~138
Lyman GH / 2005 / American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer / J Clin Oncol 23:7703~7720
Fuster D / 2008 / Preoperative staging of large primary breast cancer with [18F]fluorodeoxyglucose positron emission tomography/computed tomography compared with conventional imaging procedures / J Clin Oncol 26:4746~4751
Chua B / 2001 / Frequency and predictors of axillary lymph node metastases in invasive breast cancer / ANZ J Surg 71:723~728
Ivens D / 1992 / Assessment of morbidity from complete axillary dissection / Br J Cancer 66:136~138
Lyman GH / 2005 / American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer / J Clin Oncol 23:7703~7720
Fuster D / 2008 / Preoperative staging of large primary breast cancer with [18F]fluorodeoxyglucose positron emission tomography/computed tomography compared with conventional imaging procedures / J Clin Oncol 26:4746~4751
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