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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Objectives: Mitral regurgitation (MR) is a valvular disorder common in aged society. Treatment option available to patients with moderate to severe MR is surgical management, in the form of mitral valve repair or replacement. However, patients with MR often have both cardiac and non-cardiac comorbidities. Transcatheter mitral valve repair (TMVR) using MitraClip is introduced for these pa- tients. The aim of this study is to review recent evidence of TMVR using the leaflet repair device.
Methods: From August 2015 to March 2016, literature search was conducted with terms: MR, mi- tral valve surgery, MitraClip, percutaneous mitral valve repair, TMVR. Of total 422 publications, 26 publications including 2 systematic reviews were finally selected for detailed review. Results: Re- ported outcome for 30-day mortality was ranged from 0 to 8.0%, 1-year mortality range was 11.5 to 23.6%. 4-year outcome was reported with survival, 76.1%. Incidence rate of complications ranged from 12.6 to 22%. Effectiveness outcome was measured with New York Heart Association class and MR level improvement, of which all studies reported improvement post-procedure. Compared to mitral valve surgery, mortality and complications were lower for TMVR, and heart function im- provement was similar in both treatment in indirect comparison reviewed in systematic reviews.
Conclusion: Clinical evidence of transcather mitral valve repair using MitraClip shows safe and effective outcome for patients with moderate to severe MR. The novel procedure can provide treat- ment option for patients at high surgical risk.
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
Nishimura RA / 2014 / 2014 AHA/ACC guideline for the management of patients with valvular heart disease : executive summary : a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines / J Am Coll Cardiol 63:2438~2488
하상진 / 2014 / 승모판 폐쇄 부전증의 심초음파적 평가 / 대한내과학회지 87(4):424~428
Lim DS / 2014 / Improved functional status and quality of life in prohibitive surgical risk patients with degenerative mitral regurgitation after transcatheter mitral valve repair / J Am Coll Cardiol 64:182~192
Herrmann HC / 2012 / Effects of atrial fibrillation on treatment of mitral regurgitation in the EVEREST II(Endovascular Valve Edge-to-Edge Repair Study)randomized trial / J Am Coll Cardiol 59:1312~1319
Reichenspurner H / 2013 / Clinical outcomes through 12 months in patients with degenerative mitral regurgitation treated with the MitraClip®device in the ACCESS-EUrope Phase I trial / Eur J Cardiothorac Surg 44:280~288
하상진 / 2014 / 승모판 폐쇄 부전증의 심초음파적 평가 / 대한내과학회지 87(4):424~428
Lim DS / 2014 / Improved functional status and quality of life in prohibitive surgical risk patients with degenerative mitral regurgitation after transcatheter mitral valve repair / J Am Coll Cardiol 64:182~192
Herrmann HC / 2012 / Effects of atrial fibrillation on treatment of mitral regurgitation in the EVEREST II(Endovascular Valve Edge-to-Edge Repair Study)randomized trial / J Am Coll Cardiol 59:1312~1319
Reichenspurner H / 2013 / Clinical outcomes through 12 months in patients with degenerative mitral regurgitation treated with the MitraClip®device in the ACCESS-EUrope Phase I trial / Eur J Cardiothorac Surg 44:280~288
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