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논문 기본 정보

자료유형
학술저널
저자정보
Kyunga Kim (Samsung Medical Center) Shin-Jae Lee (Seoul National University) Soo-Heang Eo (GreenLabs Inc.) HyungJun Cho (Korea University) Jae Won Lee (Korea University)
저널정보
한국통계학회 CSAM(Communications for Statistical Applications and Methods) CSAM(Communications for Statistical Applications and Methods) 제30권 제1호
발행연도
2023.1
수록면
65 - 73 (9page)

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초록· 키워드

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Contemporary biomedical data often involve an ill-posed problem owing to small sample size and large number of multi-collinear variables. Partial least squares (PLS) method could be a plausible alternative to an ill-conditioned ordinary least squares. However, in the case of a PLS model that includes a random-effect, how to deal with a random-effect or mixed effects remains a widely open question worth further investigation. In the present study, we propose a modified multivariate PLS method implementing mixed-effect model (PLSM). The advantage of PLSM is its versatility in handling serial longitudinal data or its ability for taking a randomeffect into account. We conduct simulations to investigate statistical properties of PLSM, and showcase its real clinical application to predict treatment outcome of esthetic surgical procedures of human faces. The proposed PLSM seemed to be particularly beneficial 1) when random-effect is conspicuous; 2) the number of predictors is relatively large compared to the sample size; 3) the multicollinearity is weak or moderate; and/or 4) the random error is considerable.

목차

Abstract
1. Introduction
2. Review on PLS and the linear mixed-effect model
3. Joint modelling approach for the PLS algorithm implementing mixed effects: A modified PLS method implementing mixed-effect model (PLSM)
4. Simulation studies
5. Clinical data application
References

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