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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 105 - 112 (8page)
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Traditionally, liver transplantation for hepatocellular carcinoma with portal vein tumor thrombosis is not recommended. However, with recent developments in locoregional therapies for hepatocellular carcinoma, more aggressive treatments have been attempted for advanced hepatocellular carcinoma. Recently, various studies on locoregional therapies fordownstaging followed by living donor liver transplantation reported inspiring overall survival and recurrence-free survival of patients. These downstaging procedures included threedimensional conformal radiation therapy, trans-arterial chemoembolization, stereotactic body radiation therapy, trans-arterial radioembolization, hepatic arterial infusion chemotherapy and combinations of these therapies. Selection of the optimal downstaging protocol should depend on tumor location, biology and background liver status. The risk factors affecting outcome include pre-downstaging alpha-fetoprotein values, delta alpha-fetoprotein values, disappearance of portal vein tumor thrombosis on imaging and meeting the Milan criteria or not after downstaging. For hepatocellular carcinoma with portal vein tumor thrombosis, downstaging procedure with liver transplantation in mind would be helpful. If the reaction of the downstaged tumor is good, liver transplantation may be performed.
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참고문헌 (55)
참고문헌 신청
Mazzaferro V / 1996 / Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis / N Engl J Med 334:693~699
Yao FY / 2001 / Liver transplantation for hepatocellular carcinoma : expansion of the tumor size limits does not adversely impact survival / Hepatology 33:1394~1403
Minagawa M / 2006 / Treatment of hepatocellular carcinoma accompanied by portal vein tumor thrombus / World J Gastroenterol 12:7561~7567
Lee YH / 2014 / Vascular invasion in hepatocellular carcinoma: prevalence, determinants and prognostic impact / J Clin Gastroenterol 48:734~741
Shen J / 2018 / The prognostic value of microvascular invasion in early-intermediate stage hepatocelluar carcinoma : a propensity score matching analysis / BMC Cancer 18:278
Yao FY / 2001 / Liver transplantation for hepatocellular carcinoma : expansion of the tumor size limits does not adversely impact survival / Hepatology 33:1394~1403
Minagawa M / 2006 / Treatment of hepatocellular carcinoma accompanied by portal vein tumor thrombus / World J Gastroenterol 12:7561~7567
Lee YH / 2014 / Vascular invasion in hepatocellular carcinoma: prevalence, determinants and prognostic impact / J Clin Gastroenterol 48:734~741
Shen J / 2018 / The prognostic value of microvascular invasion in early-intermediate stage hepatocelluar carcinoma : a propensity score matching analysis / BMC Cancer 18:278
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Long-term Survival of a Patient with a Large Hepatocellular Carcinoma with Main Portal Vein Tumor Thrombosis and Spontaneous Tumor Rupture
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A Case of Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis Treated by Hepatic Arterial Infusion Chemotherapy and Radiotherapy
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Which way to go, liver resection or liver transplantation for hepatocellular carcinoma in child A liver cirrhosis.
대한외과학회 학술대회 초록집
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Bridging and Downstaging Role of Transarterial Radioembolization (TARE) for Expected Small Remnant Volume after Liver Resection in Hepatocellular Carcinoma
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Liver transplantation for combined hepatocellular carcinoma and cholangiocarcinoma in Korea
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Outcome of Total Necrosis of Hepatocellular Carcinoma after Liver Transplantation: Is It Really Totally Gone?
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Impact of Everolimus on Survival After Liver Transplantation for Hepatocellular Carcinoma
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Hepatocellular carcinoma with portal vein invasion: Non-surgical treatment
Annals of Hepato-Biliary-Pancreatic Surgery
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Systemic therapy in advanced hepatocellular carcinoma
Clinical and Molecular Hepatology
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