지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.6
- 수록면
- 56 - 68 (13page)
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초록· 키워드
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Purpose: This nationwide retrospective study aimed to examine treatment utilization patterns, including pharmacological and surgical interventions, and evaluate the long-term prognosis of trigeminal neuralgia (TN). This study also aimed to provide accurate epidemiologic information on TN.
Methods: Claims data from the Health Insurance Review and Assessment Service (HIRA) in Korea from 2007 to 2018 was utilized. Incidence rates, healthcare utilization, remission periods, and treatment durations of TN. Furthermore, pharmacological and surgical treatment patterns were also evaluated.
Results: A total of 28,669 patients were included, with an annual crude incidence rate of 7.0 per 100,000 persons. Findings showed that incidence increased with age, peaking in the 60s. Patients utilized about two healthcare institutions, with neurology having the highest visit rate among the specialties. Remission duration decreased initially but stabilized with repeated episodes. Approximately half of the patients initially received analgesics. For monotherapy, carbamazepine (CBZ, 49.3%) and gabapentin (46.9%) were the most frequently prescribed drugs. Among those patients receiving CBZ monotherapy, the mean (standard deviation) daily dose was 333.2 (167.8) mg, with a slight increase over time. Surgery was performed in 12.7% of the study population, with the ganglion procedure as the most frequent and repeated. Microvascular decompression had low reoperation rates, and fewer patients resumed medication.
Conclusions: Korean patients with TN exhibited similar demographics and epidemiologic features as those from other countries. The stable decrease in remission duration and insignificant increase in CBZ dosage over time suggests a favorable prognosis for TN. However, deviations from the international guidelines, such as the use of ineffective medications and early surgery decisions, were observed. Further education for clinicians is necessary to improve understanding and treatment of TN.
Methods: Claims data from the Health Insurance Review and Assessment Service (HIRA) in Korea from 2007 to 2018 was utilized. Incidence rates, healthcare utilization, remission periods, and treatment durations of TN. Furthermore, pharmacological and surgical treatment patterns were also evaluated.
Results: A total of 28,669 patients were included, with an annual crude incidence rate of 7.0 per 100,000 persons. Findings showed that incidence increased with age, peaking in the 60s. Patients utilized about two healthcare institutions, with neurology having the highest visit rate among the specialties. Remission duration decreased initially but stabilized with repeated episodes. Approximately half of the patients initially received analgesics. For monotherapy, carbamazepine (CBZ, 49.3%) and gabapentin (46.9%) were the most frequently prescribed drugs. Among those patients receiving CBZ monotherapy, the mean (standard deviation) daily dose was 333.2 (167.8) mg, with a slight increase over time. Surgery was performed in 12.7% of the study population, with the ganglion procedure as the most frequent and repeated. Microvascular decompression had low reoperation rates, and fewer patients resumed medication.
Conclusions: Korean patients with TN exhibited similar demographics and epidemiologic features as those from other countries. The stable decrease in remission duration and insignificant increase in CBZ dosage over time suggests a favorable prognosis for TN. However, deviations from the international guidelines, such as the use of ineffective medications and early surgery decisions, were observed. Further education for clinicians is necessary to improve understanding and treatment of TN.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
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UCI(KEPA) : I410-ECN-0102-2023-515-001792356