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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.9
- 수록면
- 89 - 95 (7page)
- DOI
- 10.22889/KJP.2023.54.3.89
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초록· 키워드
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Eupolyphaga sinensis Walker, belonging to the family Corydiidae (Blattodea), is common in Southeast Asia. Due to its richness in nutrients, E. sinensis is usually used in traditional Oriental medicine as a basic component of anticoagulant and immune-enhancing remedies. Isolation from ethanol extract of E. sinensis yielded seven compounds, two isocoumarins (1 and 2) and four phenolic compounds 3-6. Their chemical structures were elucidated as (R)-6,8-dihydroxy-3,7-dimethyl-3,4-dihydroisochromen-1-one (monaschromone) (1), (R)-3-ethyl-6,8-dihydroxy-7-methyl-3,4-dihydroisochromen-1-one (2), 3-methoxytyramine (3), hydroxyphenyl acetic acid (4), dihydroferulic acid (5), and protocatechuic acid (6), by spectroscopic analysis. Among them, compounds 3-6 were first found in E. sinensis. Additionally, the two isocoumarins, 1 and 2, exhibited biological activity such as enhancing antioxidant response element and preventing dexamethasone-induced skeletal muscle atrophy in C2C12 myotubes.
목차
Abstract
재료 및 방법
결과 및 고찰
결론
인용문헌
참고문헌 (14)
참고문헌 신청
박종희(2002) 한약백과도감(하), pp687-688. 도서출판신일상사, 서울.
Ge, G., Yu, C., Yu, B., Shen, Z., Zhang, D. and Wu, Q. (2012) Antitumor effects and chemical compositions of Eupolyphaga sinensis Walker ethanol extract. J. Ethnolpharmcol. 141:178-182.
Xie, X., Shen, W., Zhou, Y., Ma, L., Xu, D., Ding, J., He, L., Shen, B. and Zhou, C. (2020) Characterization of a polysaccharide from Eupolyphaga sinensis Walker and its effective antitumor activity via lymphocyte activation. Int. J. Biol. Macromol. 162: 31-42.
Zhang, Y., Zhan, Y., Zhang, D., Dai, B., Ma, W., Qi, J., Liu, R. and He, L. (2014) Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling. Sci. Rep. 4: 5518.
Kim, B. S., Jin, S., Park, J. Y. and Kim, S. Y. (2022) Scoping review of the medicinal effects of Eupolyphaga sinensis Walker and the underlying mechanisms. J. Ethnopharmacol. 296: 115454.
Ge, G., Yu, C., Yu, B., Shen, Z., Zhang, D. and Wu, Q. (2012) Antitumor effects and chemical compositions of Eupolyphaga sinensis Walker ethanol extract. J. Ethnolpharmcol. 141:178-182.
Xie, X., Shen, W., Zhou, Y., Ma, L., Xu, D., Ding, J., He, L., Shen, B. and Zhou, C. (2020) Characterization of a polysaccharide from Eupolyphaga sinensis Walker and its effective antitumor activity via lymphocyte activation. Int. J. Biol. Macromol. 162: 31-42.
Zhang, Y., Zhan, Y., Zhang, D., Dai, B., Ma, W., Qi, J., Liu, R. and He, L. (2014) Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling. Sci. Rep. 4: 5518.
Kim, B. S., Jin, S., Park, J. Y. and Kim, S. Y. (2022) Scoping review of the medicinal effects of Eupolyphaga sinensis Walker and the underlying mechanisms. J. Ethnopharmacol. 296: 115454.
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