지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.3
- 수록면
- 18 - 26 (9page)
이용수
초록· 키워드
오류제보하기
We developed a bioanalytical method for simultaneous determination of nine NBOMe derivatives (25H-NBOMe, 25BNBOMe, 25E-NBOMe, 25N-NBOMe, 25C-NBOH, 25I-NBOH, 25B-NBF, 25C-NBF, and 25I-NBF) in human plasma using liquid chromatography tandem mass spectrometry (LC-MS/MS). Human plasma samples were pre-treated using solid-phase extraction. Separation was achieved on a C18 column under gradient elution using a mobile phase containing 0.1% formic acid in acetonitrile and 0.1% formic acid in water at a flow rate of 0.3 mL/min. Mass detection was performed in the positive ion mode using multiple reaction monitoring. The calibration range was 1-100 ng/mL for all quantitative analytes, with a correlation coefficient greater than 0.99. The intra- and inter-day precision and accuracy varied from 0.85 to 6.92% and from 90.19 to 108.69%, respectively. The recovery ranged from 86.36 to 118.52%, and the matrix effects ranged from 27.09 to 99.72%. The stability was acceptable in various conditions. The LC-MS/MS method was validated for linearity, accuracy, precision, matrix effects, recovery and stability in accordance with the FDA guidance. The proposed method is suitable for reliable and robust routine screening and analysis of nine NBOMe derivatives in forensic field.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Metabolic profile determination of 24N-NBOMe by human liver microsomes using LC-TOF-MS
한국분석과학회 학술대회
2017 .11
-
Simultaneous determination of 61 fentanyl analogues in patch using liquid chromatography-tandem mass spectrometry (LC-MS/MS)
한국분석과학회 학술대회
2022 .05
-
Simultaneous determination of phthalate metabolites in saliva using liquid chromatography-tandem mass spectrometry (LC-MS/MS)
한국분석과학회 학술대회
2019 .11
-
Simultaneous Determination of Irinotecan and SN-38 in human plasma by LC-MS/MS method
한국분석과학회 학술대회
2023 .05
-
Development and validation of LC-MS/MS method for the simultaneous determination of Midazolam and its metabolites in human plasma
한국분석과학회 학술대회
2023 .05
-
Determination of Paclitaxel in human plasma by LC-MS/MS method
한국분석과학회 학술대회
2023 .05
-
Simultaneous determination of 19 new psycoactive substances in human plasma for quantitative analysis with LC-MS/MS
한국분석과학회 학술대회
2017 .11
-
Determination of Carbamazepine in human plasma by LC-MS/MS method
한국분석과학회 학술대회
2023 .05
-
New strategy for simultaneous analysis of cardiovascular drugs in human serum by liquid chromatography-tandem mass spectrometry
한국분석과학회 학술대회
2022 .05
-
Simultaneous profiling analysis of flavonoids by liquid chromatography-tandem mass spectrometry
한국분석과학회 학술대회
2019 .11
-
Development of the screening analysis of 50 fentanyl analogues by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
한국분석과학회 학술대회
2020 .11
-
Determination of Telmisartan in Human Plasma by LC-MS/MS Method
한국분석과학회 학술대회
2023 .05
-
Simultaneous detection method of muscle developing five monoclonal antibodies in human plasma with using LC-MS/MS
한국분석과학회 학술대회
2023 .11
-
Simultaneous determination of cyanobacterial toxins in river water by liquid chromatography-tandem mass spectrometry
한국분석과학회 학술대회
2017 .11
-
Rapid determination of propofol abusing by using hair sample with solid phase extraction and liquid chromatography-tandem mass spectrometry
한국분석과학회 학술대회
2016 .05
-
Development of method for the simultaneous determination of multi-mycotoxins in Food by LC-MS/MS
한국분석과학회 학술대회
2015 .11
-
Simultaneous Liquid Chromatography Tandem Mass Spectrometric Determination of 35 Prohibited Substances in Equine Plasma for Doping Control
Mass Spectrometry Letters
2022 .12
-
A sensitive and rapid LC-MS method for determination of berberine in human plasma
한국분석과학회 학술대회
2019 .05
-
Determination of environmental phenols in dried urine spots (DUS) by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
한국분석과학회 학술대회
2019 .11
-
Simultaneous Determination of Seventeen Amino Acids in Biological Samples Using Liquid Chromatography-Mass Spectrometry
한국분석과학회 학술대회
2022 .05
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-151-24-02-088161115