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논문 기본 정보

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학술저널
저자정보
De Cassai Alessandro (Padova University Hospital) Sella Nicolò (UOC Anesthesia and Intensive Care Unit University Hospital of Padua) Geraldini Federico (UOC Anesthesia and Intensive Care Unit University Hospital of Padua) Tulgar Serkan (Department of Anesthesiology and Reanimation Samsun Training and Research Hospital) Ahiskalioglu Ali (Atatürk University School of Medicine) Dost Burhan (5Department of Anesthesiology and Reanimation Ondokuz Mayis University Faculty of Medicine) Manfrin Silvia (6UOC Anesthesia and Intensive Care Unit Department of Medicine - DIMED University of Padua) Karapinar Yunus Emre (Department of Anesthesiology and Reanimation Ataturk University School of Medicine) Paganini Greta (UOC Anesthesia and Intensive Care Unit Department of Medicine - DIMED University of Padua) Beldagli Muzeyyen (Department of Anesthesiology and Reanimation Ondokuz Mayis University Faculty of Medicine) Luoni Vittoria (UOC Anesthesia and Intensive Care Unit Department of Medicine - DIMED University of Padua) Ordulu Busra Burcu Kucuk (Department of Anesthesiology and Reanimation Samsun Training and Research Hospital) Boscolo Annalisa (UOC Anesthesia and Intensive Care Unit University Hospital of Padua) Navalesi Paolo (University of Padua)
저널정보
대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.76 No.1
발행연도
2023.2
수록면
34 - 46 (13page)
DOI
10.4097/kja.22366

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Background: Different regional anesthesia (RA) techniques have been used for laparoscopic cholecystectomy (LC), but there is no consensus on their comparative effectiveness. Our objective was to evaluate the effect of RA techniques on patients undergoing LC using a network meta-analysis approach.Methods: We conducted a systematic review and network meta-analysis. We searched PubMed, the Cochrane Central Register of Controlled Trials (CENTRAL), Scopus, and Web of Science (Science and Social Science Citation Index) using the following PICOS criteria: (P) adult patients undergoing LC; (I) any RA single-shot technique with injection of local anesthetics; (C) placebo or no intervention; (O) postoperative opioid consumption expressed as morphine milligram equivalents (MME), rest pain at 12 h and 24 h post-operation, postoperative nausea and vomiting (PONV), length of stay; and (S) randomized controlled trials.Results: A total of 84 studies were included. With the exception of the rectus sheath block (P = 0.301), the RA techniques were superior to placebo at reducing opioid consumption. Regarding postoperative pain, the transversus abdominis plane (TAP) block (−1.80 on an 11-point pain scale) and erector spinae plane (ESP) block (−1.33 on an 11-point pain scale) were the most effective at 12 and 24 h. The TAP block was also associated with the greatest reduction in PONV.Conclusions: RA techniques are effective at reducing intraoperative opioid use, postoperative pain, and PONV in patients undergoing LC. Patients benefit the most from the bilateral paravertebral, ESP, quadratus lumborum, and TAP blocks.

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