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논문 기본 정보

자료유형
학술저널
저자정보
Choi Jin-Hui (Gimcheon Medical Center Gimcheon Republic of Korea) Koo Bon-Hoon (Department of Psychiatry Yeungnam University College of Medicine Yeungnam University Medical Center Daegu Republic of Korea) Seo Wan-Seok (Department of Psychiatry Yeungnam University College of Medicine Yeungnam University Medical Center Daegu Republic of Korea) Cheon Eun-Jin (Department of Psychiatry Yeungnam University College of Medicine Yeungnam University Medical Center Daegu Republic of Korea) Sung Hyung-Mo (Department of Psychiatry Soonchunhyang University College of Medicine Soonchunhyang University Medical Center Gumi Republic of Korea) Kim Ji Yean (Department of Psychology Yeungnam University Medical Center Daegu Republic of Korea) Jeong Hyun-Seok (Department of Psychology Yeungnam University Medical Center Daegu Republic of Korea) Kim Younggyo (Department of Psychology Yeungnam University Medical Center Daegu Republic of Korea) Kim Hye-Geum (Department of Psychiatry Yeungnam University College of Medicine Yeungnam University Medical Center Daegu Republic of Korea)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제20권 제2호
발행연도
2023.2
수록면
109 - 119 (11page)
DOI
10.30773/pi.2022.0223

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Objective This study aimed to explore the characteristics and factors related to changes in cognitive function in vulnerable individuals with cognitive impairment during the coronavirus disease 2019 (COVID-19) pandemic.Methods Among patients who visited a local university hospital with subjective cognitive complaints, those who had been tested for cognitive function at least once after the onset of COVID-19 and tested regularly at least three times within the last 5 years were included (1st, the initial screening; 2nd, the test immediately before the COVID-19 pandemic; 3rd, the most recent test after the pandemic). Finally, 108 patients were included in this study. They were divided into groups according to whether the Clinical Dementia Rating (CDR) was maintained/improved and deteriorated. We investigated the characteristics of the changes in cognitive function and related factors during COVID-19.Results When comparing CDR changes before and after COVID-19, there was no significant difference between the two groups (p=0.317). Alternatively, the main effect of the time when the test was conducted was significant (p<0.001). There was also a significant difference in the interaction between the groups and time. When the effect of the interaction was analyzed, the CDR score of the maintained/ improved group significantly decreased before COVID-19 (1st–2nd) (p=0.045). After COVID-19 (2nd–3rd), the CDR score of the deteriorated group was significantly higher than that of the maintained/improved group (p<0.001). Mini-Mental State Examination recall memory and changes in activity during COVID-19 were significantly associated with CDR deterioration.Conclusion Memory dysfunction and decreased activity during the COVID-19 pandemic are strongly related to the deterioration of cognitive impairment.

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