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논문 기본 정보

자료유형
학술저널
저자정보
Kim Jae-Min (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Kang Hee-Ju (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Kang Hee-Ju (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Kim Ye-Jin (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Kim Ju-Wan (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Kim Ju-Wan (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Choi Wonsuk (Department of Internal Medicine Chonnam National University Hwasun Hospital Chonnam National University Medical School Hwasun Republic of Korea) Lee Ju-Yeon (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Lee Ju-Yeon (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Kim Sung-Wan (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Kim Sung-Wan (Department of Psychiatry Chonnam National University Medical School Gwangju Republic of Korea) Kim Jung-Chul (Department of Surgery Chonnam National University Medical School and Hospital Gwangju Republic of Korea) Ahn Youngkeun (Department of Cardiology Chonnam National University Medical School Gwangju Republic of Korea) Jeong Myung Ho (Department of Cardiology Chonnam National University Medical School Gwangju Republic of Korea)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제20권 제4호
발행연도
2023.4
수록면
369 - 373 (5page)
DOI
10.30773/pi.2022.0372

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초록· 키워드

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Objective This study investigated associations of life stressors and serum ghrelin levels with suicidal ideation (SI), and evaluated the potential mediating effect of ghrelin on associations between life stressors and SI in patients with acute coronary syndrome (ACS).Methods In total, 969 ACS patients recruited from a tertiary university hospital in Korea within 2 weeks of disease onset were evaluated in terms of life stressors (using the List of Threatening Events Questionnaire), serum ghrelin levels, and SI (using the “suicidal thoughts” item of the Montgomery–Asberg Depression Rating Scale). Covariates included sociodemographics, depression, vascular risk factors, and disease severity. After 1 year, 711 patients were re-evaluated in terms of SI; logistic regression was performed with adjustment for covariates.Results Life stressors were significantly associated with SI at baseline and follow-up. Serum ghrelin showed no such associations, but high levels thereof mediated associations of life stressors with SI; significant interaction terms were also observed after adjustment for covariates.Conclusion By evaluating life stressors and serum ghrelin levels, clinical prediction of SI in the acute and chronic phases of ACS could be improved.

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