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자료유형
학술저널
저자정보
Pao-Huan Chen (Taipei Medical University) Chun-Ming Shih (Taipei Medical University) Chi-Kang Chang (Taipei City Hospital) Chia-Pei Lin (Taipei Medical University) Yung-Han Chang (Taipei Medical University) Hsin-Chien Lee (Taipei Medical University) El-Wui Loh (Taipei Medical University)
저널정보
대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제21권 제2호
발행연도
2023.5
수록면
262 - 270 (9page)
DOI
10.9758/cpn.2023.21.2.262

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Objective: Predicting disease relapse and early intervention could reduce symptom severity. We attempted to identify potential indicators that predict the duration to next admission for an acute affective episode in patients with bipolar I disorder. Methods: We mathematically defined the duration to next psychiatric admission and performed single-variate regressions using historical data of 101 patients with bipolar I disorder to screen for potential variables for further multivariate regressions. Results: Age of onset, total psychiatric admissions, length of lithium use, and carbamazepine use during the psychiatric hospitalization contributed to the next psychiatric admission duration positively. The all-in-one found that hyperlipidemia during the psychiatric hospitalization demonstrated a negative contribution to the duration to next psychiatric admission; the last duration to psychiatric admission, lithium and carbamazepine uses during the psychiatric hospitalization, and heart rate on the discharge day positively contributed to the duration to next admission. Conclusion: We identified essential variables that may predict the duration of bipolar I patients’ next psychiatric admission. The correlation of a faster heartbeat and a normal lipid profile in delaying the next onset highlights the im portance of managing these parameters when treating bipolar I disorder.

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