지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.2
- 수록면
- 23 - 31 (9page)
- DOI
- https://doi.org/10.5021/ad.22.070
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초록· 키워드
오류제보하기
Background: The advent of fractionated picosecond (ps) lasers has provided an opportunityto explore new ways of creating microinjuries in the skin to induce skin rejuvenation.
Objective: To compare the efficacy and safety of diffractive optical element (DOE)-assistedps neodymium: yttrium-aluminum-garnet (Nd:YAG) lasers with 532-nm and 1,064-nmwavelengths (532-nm and 1,064-nm Nd:YAG P-DOE) using a novel fractional handpiece forthe treatment of photoaged skin.
Methods: An ex vivo guinea pig skin experiment was performed by evaluating the histologyof the skin after 532-nm Nd:YAG P-DOE irradiation. A randomized, prospective, split-facestudy was performed on eight subjects with 532-nm and 1,064-nm Nd:YAG P-DOE.
Results: Based on the histological evaluation using ex vivo guinea pig skin, a reasonablesafety profile and the potential to generate effective skin rejuvenation was observed usingthe 532-nm Nd:YAG P-DOE. Results demonstrated that both 532- and 1,064-nm Nd:YAGP-DOE were similarly effective in improving skin texture and skin pores; however, 532-nmNd:YAG P-DOE was more effective in treating dyspigmentation.
Conclusion: At a preliminary level, this study revealed that 532-nm and 1,064-nm ps Nd:YAGlasers using DOE fractional technology may improve photoaged skin. In conclusion, 532-nmNd:YAG P-DOE may be especially beneficial for skin with epidermal pigmentary lesions.
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