Computed tomography-guided Gasserian ganglion interventions for cancer-related facial pain in patients with complex anatomy: Insights and recommendations

Ale Ismael González-Casarez1; Santamaría-Montaño Germán Gerardo; Plancarte-Sánchez Ricardo; Guillén-Núñez María Rocío; Juárez-Lemus Ángel Manuel; Hernández-Porras Berenice Carolina; Samano-García Marcela; Rocha-Romero Andrés

doi:10.17085/apm.22225

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저자정보: Ale Ismael González-Casarez1 (Department of Pain Medicine National Cancer Institute Mexico City 2Department of Anesthesia and Pain Medicine) Santamaría-Montaño Germán Gerardo (Department of Anesthesia and Pain Medicine Hospital General del Estado Dr. Ernesto Ramos Bours Hermosillo Mexico) Plancarte-Sánchez Ricardo (Department of Pain Medicine National Cancer Institute Mexico City) Guillén-Núñez María Rocío (Department of Pain Medicine National Cancer Institute Mexico City) Juárez-Lemus Ángel Manuel (Department of Pain Medicine National Cancer Institute Mexico City) Hernández-Porras Berenice Carolina (Department of Pain Medicine National Cancer Institute Mexico City) Samano-García Marcela (Department of Pain Medicine National Cancer Institute Mexico City) Rocha-Romero Andrés (Department of Anesthesia and Pain Medicine Centro Nacional de Rehabilitación Hospital de Trauma San José Costa Rica)

저널정보: 대한마취통증의학회(구 대한마취과학회) Anesthesia and Pain Medicine Anesthesia and Pain Medicine Vol.18 No.2

발행연도: 2023.4

수록면: 132 - 138 (7page)

DOI: 10.17085/apm.22225

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Background: The Gasserian ganglion is a well-known target for facial pain management, and patients with cancer present an anatomical challenge owing to tumor progression or treatment itself. Computed tomography (CT) is an alternative method for guiding these procedures.Methods: This was an observational retrospective analysis of patients with cancer-related facial pain who underwent CT-guided Gasserian ganglion interventions using local anesthetics, local anesthetics with steroids, phenol, and radiofrequency. Demographic, clinical, and procedure-related variables were collected from January 1, 2015, to December 30, 2018, at the National Cancer Institute. Data distribution was determined using the Kolmogorov–Smirnov test. A paired sample t-test (with a cut-off of P < 0.05 for statistical significance) was used for comparing outcome.Results: We observed a significant reduction in numerical rating scale (NRS) and douleur neuropathique 4 (DN4) scores from 7.6 ± 1.4 and 4.4 ± 1.4 to 3.2 ± 2.0 and 2.2 ± 1.4 points, respectively (P < 0.001). After the procedure, 70.8% of the patients were satisfied; 16.7% were very satisfied, and 12.5% were unsatisfied. No intra- or postoperative complications were observed. The most common neoplasms were head and neck tumors (83.3%).Conclusions: Our data suggest that CT guidance is an effective and safe option for managing cancer-related facial pain in patients with complex anatomy, resulting in a significant reduction in pain, high satisfaction rates, and no mechanical complications. Future research should aim to refine the role of CT guidance in multimodal pain management in this population.

#Cancer pain #Facial pain #Neoplasm #Trigeminal ganglion

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Ale Ismael González-Casarez1

소속기관 Department of Pain Medicine National Cancer Institute Mexico City 2Department of Anesthesia and Pain Medicine

주요연구분야 의약학 > 임상의학 > 마취과학

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Santamaría-Montaño Germán Gerardo

소속기관 Department of Anesthesia and Pain Medicine Hospital General del Estado Dr. Ernesto Ramos Bours Hermosillo Mexico

주요연구분야 의약학 > 임상의학 > 마취과학

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Plancarte-Sánchez Ricardo