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논문 기본 정보

자료유형
학술저널
저자정보
Kerrebijn Isabel (Flosonics Medical, Toronto, ON, Canada) Atwi Sarah (Flosonics Medical, Toronto, ON, Canada) Elfarnawany Mai (Flosonics Medical, Toronto, ON, Canada) Eibl Andrew M. (Flosonics Medical, Toronto, ON, Canada) Eibl Joseph K. (Flosonics Medical, Toronto, ON, Canada) Taylor Jenna L. (Human Integrative and Environmental Physiology Laboratory, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA) Kim Chul-Ho (Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, USA) Johnson Bruce D. (Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, USA) Kenny Jon-Émile S. (Flosonics Medical, Toronto, ON, Canada)
저널정보
대한중환자의학회 Acute and Critical Care Acute and Critical Care Vol.39 No.1
발행연도
2024.2
수록면
162 - 168 (7page)
DOI
10.4266/acc.2023.01095

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Background: Using peripheral arteries to infer central hemodynamics is common among hemodynamic monitors. Doppler ultrasound of the common carotid artery has been used in this manner with conflicting results. The aim of this study was to investigate the relationship between changing common carotid artery Doppler measures and stroke volume (SV). We hypothesized that correlation between SV and carotid Doppler would improve with larger numbers of consecutively-averaged cardiac cycles. Methods: Twenty-seven healthy volunteers were recruited and studied in a physiology laboratory. Carotid artery Doppler pulse was measured with a wearable, wireless ultrasound during central hypovolemia and resuscitation induced by a stepped lower body negative pressure protocol. The change in maximum velocity time integral (VTI) and corrected flow time of the carotid artery (ccFT) were compared with changing SV using repeated measures correlation. Results: In total, 73,431 cardiac cycles were compared across 27 subjects. There was a strong linear correlation between changing SV and carotid Doppler measures during simulated hemorrhage (repeated-measures linear correlation [Rrm]=0.91 for VTI; 0.88 for ccFT). This relationship improved with larger numbers of consecutively-averaged cardiac cycles. For ccFT, beyond four consecutively-averaged cardiac cycles the correlation coefficient remained strong (i.e., Rrm of at least 0.80). For VTI, the correlation coefficient with SV was strong for any number of averaged cardiac cycles. For both ccFT and VTI, Rrm remained stable around 25 consecutively-averaged cardiac cycles. Conclusions: Using a wearable carotid Doppler ultrasound 73,431 cardiac cycles were compared to SV during central volume loss and resuscitation induced.

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