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논문 기본 정보

자료유형
학술저널
저자정보
Park Sooin (Department of Anesthesiology and Pain Medicine, National Police Hospital, Seoul, Korea) Longhao Piao (Biomedical Center, Korea University Medical Center, Seoul, Korea) Yoon Seung Zhoo (Department of Anesthesiology and Pain Medicine, Anam Hospital, Korea University College of Medicine, Seoul, Korea) Choi Yoon Ji (Department of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, Ansan, Korea) Park GeneHyun (Department of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, Ansan, Korea) Xu Guo-Shan (Department of Anesthesiology, Yanbian University Hospital, Yanbian, China)
저널정보
조선대학교 의학연구원 Medical Biological Science and Engineering Medical Bilogical Science and Engineering Vol.7 No.1
발행연도
2024.1
수록면
9 - 15 (7page)
DOI
10.30579/mbse.2024.7.1.9

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In general, body temperature decreases during anesthesia. However, we found that body tem perature increased during reconstructive surgery for microtia involving autogenous costal car tilage harvesting. Therefore, we aimed to compare changes in body temperature and cytokine concentrations between two types of simulation surgery (embedding and elevation) using rat models. Two simulation surgeries were performed on male Sprague-Dawley rats (8 weeks old, n=25). The 8th and 9th costal cartilages (1-1.5 cm long) were harvested in the first operation, but not in the second. We compared changes in body temperature, interleukin-6 (IL-6) levels, and tumor necrosis factor-alpha (TNF-a) concentrations between the first and second opera tions. Body temperatures increased in the costal cartilage harvest group compared with another group. Body temperature changes between the two groups were statistically significant at 5 to 6 h after anesthesia in rats (p<0.05). However, IL-6 and TNF-a levels were not significantly dif ferent between the two rat groups. As a result of this study, it was confirmed that the harvesting costal cartilage increased the body temperatures of rats during surgery. However, there were no significant differences in cytokine concentrations. Further research is required in the future to determine the cause.

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