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논문 기본 정보

자료유형
학술저널
저자정보
Siyeon Jang (Dongguk University-Seoul) Hyeonjin Lee (Dongguk University-Seoul) Hyeon Woo Kim (Dongguk University-Seoul) Minjae Baek (Dongguk University-Seoul) Sanghyun Jung (Dongguk University-Seoul) Sun Jung Kim (Dongguk University-Seoul)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.48 No.4
발행연도
2024.7
수록면
347 - 353 (7page)

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초록· 키워드

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Ginsenosides in ginseng are known for their potential health benefits, including antioxidant properties and their potential to exhibit anticancer effects. Besides a various range of coding genes, ginsenosides impose their efficacy by targeting noncoding RNAs. Long noncoding RNA (lncRNA) has gained significant attention from both basic and clinical oncology fields due to its involvement in various cancer cell activities such as proliferation, apoptosis, metastasis, and autophagy. These events can be achieved either by lncRNA alone or in association with microRNAs or proteins. This review aims to summarize the diverse activities of lncRNAs that are regulated by ginsenosides, focusing on their role in regulating target genes through signaling pathways in human diseases. We highlight the results of studies on the expression profiles of lncRNAs induced by ginsenosides in efforts to inhibit cancer cell proliferation. Finally, we discuss the potential and challenges of utilizing lncRNAs as diagnostic markers for disease treatment.

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ABSTRACT
1. Introduction
2. Ginsenodides, lncRNAs, and diseases
3. Regulatory mechanism of lncRNAs dysregulated by ginsenosides
4. Conclusions
References

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