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논문 기본 정보

자료유형
학술저널
저자정보
ZEB ALAM (가천대학교) Khan Namrah (Riphah International University, Pakistan) Shah Fawad Ali (Prince Sattam Bin Abdulaziz University, Saudi Arabia) Ullah Aziz (Pukyong National University) Choi Ho-Ik (College of Pharmacy, Institute of Pharmaceutical Sciences and Technology, Hanyang University ERICA) 류정수 (한양대학교) Bae Yumi (College of Pharmacy, Institute of Pharmaceutical Sciences and Technology, Hanyang University ERICA) 맹한주 (가천대학교) 김원동 (한양대학교) Kim Jin-Ki (Hanyang University)
저널정보
한국약제학회 Journal of Pharmaceutical Investigation Journal of Pharmaceutical Investigation Vol.54 No.3
발행연도
2024.5
수록면
283 - 316 (34page)
DOI
10.1007/s40005-024-00664-z

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Background Sexually transmitted infections (STIs) are a major public health concern, accounting for millions of new infections each year and a high mortality rate. Acute diseases and infertility are also associated with STIs that pose a substantial economic burden. Antimicrobial drug resistance, suboptimal drug concentrations at the infection site, and potential adverse effects are some of the limitations of conventional therapies for STIs. Nanotechnology-based approaches offer promising alternatives to treat and prevent STIs. Several nanoplatforms such as lipid, polymer, lipid-polymer hybrid, and inorganic nanoparticles (NPs) have been developed to overcome the shortcomings of conventional therapy and enhance the efficacy and selectivity of drugs toward STIs. Area covered With an aim to consolidate emerging nanotechnology-based efforts in combating STIs, this review highlights the merits and applications of NPs for the treatment of common bacterial, viral, and parasitic STIs. In addition, NPs-based approaches such as nanovaccines and topical nanomicrobicides to prevent STIs were also reviewed. Expert opinion The data presented in this review demonstrate the exceptional promise of NPs for STI therapy and prevention. These nanotechnology-based approaches may help reduce global health burdens in future clinical outlook by producing socially acceptable and clinically useful products for STIs.

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