지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.4
- 수록면
- 167 - 175 (9page)
- DOI
- https://doi.org/10.5483/BMBRep.2024-0019
이용수
초록· 키워드
오류제보하기
Cancer progression is driven by genetic mutations, environmentalfactors, and intricate interactions within the tumor microenvironment(TME). The TME comprises of diverse cell types,such as cancer cells, immune cells, stromal cells, and neuronalcells. These cells mutually influence each other through variousfactors, including cytokines, vascular perfusion, and matrixstiffness. In the initial or developmental stage of cancer, neurotrophicfactors such as nerve growth factor, brain-derived neurotrophicfactor, and glial cell line-derived neurotrophic factorare associated with poor prognosis of various cancers by communicatingwith cancer cells, immune cells, and peripheralnerves within the TME. Over the past decade, research has beenconducted to prevent cancer growth by controlling the activationof neurotrophic factors within tumors, exhibiting a novelattemt in cancer treatment with promising results. More recently,research focusing on controlling cancer growth through regulationof the autonomic nervous system, including the sympatheticand parasympathetic nervous systems, has gained significantattention. Sympathetic signaling predominantly promotestumor progression, while the role of parasympathetic signalingvaries among different cancer types. Neurotransmitters releasedfrom these signalings can directly or indirectly affect tumor cellsor immune cells within the TME. Additionally, sensory nervesignificantly promotes cancer progression. In the advanced stageof cancer, cancer-associated cachexia occurs, characterized bytissue wasting and reduced quality of life. This process involvesthe pathways via brainstem growth and differentiation factor15-glial cell line-derived neurotrophic factor receptor alpha-likesignaling and hypothalamic proopiomelanocortin neurons. Ourreview highlights the critical role of neurotrophic factors aswell as central nervous system on the progression of cancer,offering promising avenues for targeted therapeutic strategies.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Tumor Microenvironment Modulating Functional Nanoparticles for Effective Cancer Treatments
조직공학과 재생의학
2022 .04
-
T Cell-mimicking Nanoparticles for Cancer Immunotherapy
한국고분자학회 학술대회 연구논문 초록집
2021 .04
-
Role of extrinsic physical cues in cancer progression
BMB Reports
2023 .05
-
Acceleration of Cancer Progression and Resistance of Cancer Therapies According to the Polymer Type and Physical Properties
한국고분자학회 학술대회 연구논문 초록집
2023 .04
-
Microsensor for Cancer Detection and MEMS Actuator for Cancer Therapy
Transactions on Electrical and Electronic Materials
2023 .02
-
In Vitro Modeling of the Tumor Microenvironment in Tumor Organoids
조직공학과 재생의학
2020 .01
-
The Use of Normal Stem Cells and Cancer Stem Cells for Potential Anti-Cancer Therapeutic Strategy
조직공학과 재생의학
2018 .01
-
The force awakens: metastatic dormant cancer cells
Experimental and Molecular Medicine
2020 .01
-
암 생존자의 질병관련 특성과 암 대처가 외상 후 성장에 미치는 영향
보건정보통계학회지
2015 .01
-
Combination of anti-angiogenic therapy and immune checkpoint blockade normalizes vascular-immune crosstalk to potentiate cancer immunity
Experimental and Molecular Medicine
2020 .09
-
Exosome-derived microRNAs in cancer metabolism: possible implications in cancer diagnostics and therapy
Experimental and Molecular Medicine
2017 .01
-
Immune Cell Membrane-Coated Lipid Nanoparticles for Simultaneous Cancer Cell Death and Immune Cell Activation
한국생물공학회 학술대회
2023 .04
-
Cancer immunotherapy: special issue of BMB Reports in 2021
BMB Reports
2021 .01
-
Co-Culturing Cancer Cells and Normal Cells in a Biochip under Electrical Stimulation
BioChip Journal
2018 .01
-
3D printing of a patient-specific brain cancer-on-a-chip
대한기계학회 춘추학술대회
2017 .11
-
Proteomic Studies of Cancer Stem Cells in HT-29 Human Colorectral Cancer Cell Line
한국생물공학회 학술대회
2015 .04
-
Potential roles of reactive oxygen species derived from chemical substances involved in cancer development in the female reproductive system
BMB Reports
2018 .01
-
Prediction of Metabolites from Cancer-associated Fibroblasts that Control Cancer Cells
한국생물공학회 학술대회
2022 .09
-
Analyzing Brain Cancer Survivability Using SEER(Surveillance, Epidemiology, and End Results Program) Data with method of Kaplan Meier
대한인간공학회 학술대회논문집
2015 .10
-
Continuous Sorting and Washing of Cancer Cells from Blood Cells by Hydrophoresis
BioChip Journal
2016 .01
최근 본 자료
댓글(0)
0