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논문 기본 정보

자료유형
학술저널
저자정보
Konstantin Semash (Department of HPB Surgery and Liver Transplantation #1, Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov, Tashkent, UzbekistanDe) Timur Dzhanbekov (Department of HPB Surgery and Liver Transplantation #1, Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov, Tashkent, UzbekistanDe) Mirshavkat Akbarov (Department of HPB Surgery and Liver Transplantation #1, Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov, Tashkent, UzbekistanDe) Miraziz Mirolimov (Department of HPB Surgery and Liver Transplantation #1, Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov, Tashkent, Uzbekistan) Azimjon Usmonov (Department of HPB Surgery and Liver Transplantation #1, Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov, Tashkent, Uzbekistan) Navruz Razzokov (Department of HPB Surgery and Liver Transplantation #1, Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov, Tashkent, Uzbekistan) Ziyodulla Primov (Department of HPB Surgery and Liver Transplantation #1, Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov, Tashkent, Uzbekistan) Temurbek Gaybullaev (Department of HPB Surgery and Liver Transplantation #1, Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov, Tashkent, UzbekistanDe) Sardor Yigitaliev (Department of HPB Surgery and Liver Transplantation #1, Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov, Tashkent, Uzbekistan)
저널정보
대한이식학회 Clinical Transplantation and Research Clinical Transplantation and Research 제38권 제2호
발행연도
2024.6
수록면
116 - 127 (12page)
DOI
10.4285/ctr.24.0013

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초록· 키워드

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Background: Living donor liver transplantation (LDLT) is an effective treatment for patients with end-stage liver disease. This study was performed to evaluate the outcomes of the initial series of LDLT procedures performed in the Republic of Uzbekistan and to demonstrate that liver transplantation is viable under the conditions in this country. Methods: Between October 2021 and December 2023, we performed 40 LDLTs. We evaluated both immediate and long-term outcomes. Results: Thrombosis of the hepatic artery developed in one case (2.5%). Arterial anastomotic stenoses were diagnosed in three cases (7.5%) and were successfully treated with endovascular balloon vasodilation. Splenic artery steal syndrome arose in three patients (7.5%) and was managed with endovascular embolization of the splenic artery. One patient (2.5%) developed portal vein thrombosis. Portal vein stenosis occurred in two patients (5%) at 10 months posttransplantation and was addressed with endovascular balloon angioplasty, yielding good clinical outcomes. Biliary complications were observed in 45% of the cases, with bile leakages accounting for 89% of these issues and strictures of the biliary anastomoses for 11%. The in-hospital mortality rate was 12.5%. Conclusions: Our research findings and analysis of complications align with the international literature, and the results are deemed acceptable during this implementation phase of the liver transplantation program. Accordingly, liver transplantation is feasible in the Republic of Uzbekistan; however, improvements in surgical and therapeutic methods are necessary to minimize the development of both early and late postoperative complications.

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