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논문 기본 정보

자료유형
학술저널
저자정보
Kim Ji Yeon (Department of Anesthesiology and Pain Medicine, CHA Gangnam Medical Center, CHA University School of Medicine) Moon Young-Jin (Department of Anesthesiology and Pain Medicine, Laboratory for Cardiovascular Dynamics, Asan Medical Center, University of Ulsan College of Medicine) Lee Changjin (Department of Anesthesiology and Pain Medicine, CHA Bundang Medical Center, CHA University, Seongnam,) Kim Jin Ho (Department of Anesthesiology and Pain Medicine, CHA Bundang Medical Center, CHA University School of Medicine) Park Junghyun (Department of Anesthesiology and Pain Medicine, CHA Bundang Medical Center, CHA University School of Medicine) Kim Jung-Won (Department of Anesthesiology and Pain Medicine, Laboratory for Cardiovascular Dynamics, CHA Bundang Medical Center, CHA University School of Medicine)
저널정보
대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.77 No.2
발행연도
2024.4
수록면
217 - 225 (9page)
DOI
10.4097/kja.23266

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Background: Liver transplantation (LT) increases the heart and vessel workload in patients with cirrhotic cardiomyopathy. While the interaction of the left ventricle (LV) with the arterial system (ventriculoarterial coupling, VAC) is a key determinant of cardiovascular performance, little is known about changes in VAC after LT. Therefore, we evaluated the relationship between VAC after LT and cardiovascular outcomes. Methods: 344 consecutive patients underwent echocardiographic assessments before and within 30 days after LT. Non-invasive arterial elastance (Ea), LV end-systolic elastance (Ees), and LV end-diastolic elastance (Eed) were calculated. The postoperative outcomes included the development of major adverse cardiovascular events (MACE) and the length of stay in the intensive care unit and hospital.Results: A total of 240 patients were included in the analyses. After LT, Ea increased by 16% (P < 0.001), and Ees and contractility index of systolic velocity (S') increased by 18% (P < 0.001) and 7% (P < 0.001), respectively. The Eed increased by 6% (P < 0.001). The VAC remained unchanged (0.56 to 0.56, P = 0.912). Of these patients, 29 had MACE, and those with MACE had significantly higher postoperative VAC. Additionally, a higher postoperative VAC was an independent risk factor for a longer postoperative hospital stay (P = 0.038). Conclusions: These data suggest that ventriculoarterial decoupling is associated with poor postoperative outcomes after LT.

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