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논문 기본 정보

자료유형
학술저널
저자정보
송우심 (宋雨芯) (Key Laboratory of Cosmetics, China National Light Industry, School of Light Industry Science and Engineering, Beijing Technology and Business University) 정문옥 (Key Laboratory of Cosmetics, China National Light Industry, School of Light Industry Science and Engineering, Beijing Technology and Business University) 손금월 (Key Laboratory of Cosmetics, China National Light Industry, School of Light Industry Science and Engineering, Beijing Technology and Business University) 필영현 (Zhejiang Yige Enterprise Management Group Co., Ltd) 유금준 (Zhejiang Yige Enterprise Management Group Co., Ltd.) 대효염 (Zhejiang Yige Enterprise Management Group Co., Ltd) 하총분 (Key Laboratory of Cosmetics, China National Light Industry, School of Light Industry Science and Engineering, Beijing Technology and Business University) 하화명 (Key Laboratory of Cosmetics, China National Light Industry, School of Light Industry Science and Engineering, Beijing Technology and Business University) 가염 (Key Laboratory of Cosmetics, China National Light Industry, School of Light Industry Science and Engineering, Beijing Technology and Business University)
저널정보
한국피부과학연구원 아시안뷰티화장품학술지 아시안뷰티화장품학술지 제22권 제2호
발행연도
2024.6
수록면
197 - 209 (13page)

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Purpose: According to the life rhythm derived from the ancient Chinese medicine book Huangdi Neijing, female growth and development culminates between the age of 22-28, with strong muscles, bones and vigorous hair. To investigate the characteristics of facial lipid profile in oily skin of female at different developmental stages classified based on seven-year rhythm, and to provide the mechanistic insight into the aging theory of Huangdi Neijing. Methods: The facial lipid composition of two groups of healthy women with oily skin (O1 group: age of 22-28; O2 group: age of 29-35) was analyzed by ultra-performance liquid chromatography-quadrupole tandem time-of-flight mass spectrometry (UPLC-QTOF-MS). Differential lipids between O1 and O2 groups were identified using an orthogonal partial least squares discriminant analysis (OPLS-DA) model. Results: No significant difference in skin barrier function was found between the O1 and O2 groups. In contrast, skin elasticity and skin radiance displayed significant changes, with the O2 group showing decreased skin elasticity and dull skin, which is consistent with the description in Huangdi Neijing. In terms of lipid profile, among eight lipid main classes, seven lipid classes [FA], [GL], [GP], [PK], [PR], [SP] and [ST] showed significantly higher relative levels in the O2 group (p<0.05). Among the differential lipid species, myriocin, erucamide, phosphatidylserine, flavonoid compounds, and sphinganine were significantly and negatively correlated with skin elasticity (R2) and skin radiance (ITA) (p<0.05). Conclusion: The seven lipid species identified are important for targeting markers of skin aging and developing cosmetics that maintain skin elasticity and color.

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